- claim_text
Using in vivo two-photon calcium imaging in layers 2/3 and 4 in mouse V1, we reveal that locomotion increases the activity of vasoactive intestinal peptide (VIP), somatostatin (SST) and parvalbumin (PV)-positive interneurons during visual stimulation, challenging the disinhibition model.
- raw_fields
{
"n": null,
"doi": "10.7554/elife.14985",
"year": "2016",
"claim": "Using in vivo two-photon calcium imaging in layers 2/3 and 4 in mouse V1, we reveal that locomotion increases the activity of vasoactive intestinal peptide (VIP), somatostatin (SST) and parvalbumin (PV)-positive interneurons during visual stimulation, challenging the disinhibition model.",
"title": null,
"journal": "eLife",
"cite_key": "Pakan2016",
"evidence": "Behavioral-state modulation of inhibition is context-dependent and cell type specific in mouse visual cortex",
"effect_size": null,
"text_access": "abstract_only",
"first_author": "Pakan",
"study_system": "mouse V1",
"_source_cluster": "cluster_06_disinhibition_circuit",
"author_list_short": "Pakan, Lowe, Dylda",
"replication_status": "contested",
"_source_cluster_index": 12,
"claim_source_sentence": "Using in vivo two-photon calcium imaging in layers 2/3 and 4 in mouse V1, we reveal that locomotion increases the activity of vasoactive intestinal peptide (VIP), somatostatin (SST) and parvalbumin (PV)-positive interneurons during visual stimulation, challenging the disinhibition model.",
"replication_evidence_dois": [
"10.1016/j.cell.2014.01.050",
"10.1016/j.neuron.2018.03.037"
],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-acf576c0a2ed"
]
- source_span
Using in vivo two-photon calcium imaging in layers 2/3 and 4 in mouse V1, we reveal that locomotion increases the activity of vasoactive intestinal peptide (VIP), somatostatin (SST) and parvalbumin (PV)-positive interneurons during visual stimulation, challenging the disinhibition model.
- evidence_refs
[
{
"ref": "paper:paper-acf576c0a2ed"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}