Details

scope
awake mouse CA1-subiculum, VIP-Cre two-photon imaging + slice
section_id
section_10
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json
effect_size
VIP-LRPs: decreased activity during theta-run, increased during quiet wake, no SWR coupling
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-10-oscillatory-dynamics
source_kind
review_finding
source_path
evidence/section_10_evidence_package.json
source_span
In awake mice, VIP-LRPs decrease their activity during theta-run epochs and are more active during quiet wakefulness but not coupled to sharp-wave ripples.
study_system
awake mouse CA1-subiculum, VIP-Cre two-photon imaging + slice
section_title
Oscillatory Dynamics and Temporal Coordination
evidence_summary
In vivo two-photon Ca2+ imaging, anatomical tracing, and slice patch-clamp in awake mice; comparison across brain states.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
single-study
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-10-oscillatory-dynamics
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
A class of long-range VIP+ projection neurons (VIP-LRPs) connecting CA1 to subiculum decreases activity during theta-run epochs, is more active during quiet wakefulness, and is not coupled to sharp-wave ripples in awake mice—contrasting with local VIP-IS cells.
raw_fields
{
  "n": null,
  "doi": "10.1038/s41467-018-07162-5",
  "pmid": "30487571",
  "year": "2018",
  "claim": "A class of long-range VIP+ projection neurons (VIP-LRPs) connecting CA1 to subiculum decreases activity during theta-run epochs, is more active during quiet wakefulness, and is not coupled to sharp-wave ripples in awake mice—contrasting with local VIP-IS cells.",
  "pmcid": "PMC6261953",
  "title": "Connectivity and network state-dependent recruitment of long-range VIP-GABAergic neurons in the mouse hippocampus.",
  "authors": "",
  "journal": "",
  "cite_key": "Francavilla2018a",
  "evidence": "In vivo two-photon Ca2+ imaging, anatomical tracing, and slice patch-clamp in awake mice; comparison across brain states.",
  "cluster_id": "cluster_09_oscillations",
  "effect_size": "VIP-LRPs: decreased activity during theta-run, increased during quiet wake, no SWR coupling",
  "figure_data": [],
  "text_access": "fulltext",
  "study_system": "awake mouse CA1-subiculum, VIP-Cre two-photon imaging + slice",
  "cited_by_count": 99,
  "_source_cluster": "cluster_09_oscillations",
  "replication_status": "single-study",
  "_source_cluster_index": 16,
  "claim_source_sentence": "In awake mice, VIP-LRPs decrease their activity during theta-run epochs and are more active during quiet wakefulness but not coupled to sharp-wave ripples.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "VIP-LRPs decrease their activity during theta-run epochs and are more active during quiet wakefulness but not coupled to sharp-wave ripples."
}
source_refs
[
  "paper:paper-c5dc6d520729"
]
evidence_refs
[
  {
    "ref": "paper:paper-c5dc6d520729"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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