Details

scope
mouse primary visual cortex excitatory neurons, Patch-seq + complete-morphology reconstruction
section_id
section_02
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-02-anatomy-primer
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
study_system
mouse primary visual cortex excitatory neurons, Patch-seq + complete-morphology reconstruction
section_title
2. Mouse-cortex anatomy primer — areal map, layer structure, projection-class nomenclature (IT / PT / CT), tools available for E→E dissection (paired patch, Cre lines, two-photon-targeted patch, optogenetics, EM reconstruction)
evidence_summary
Coordinated Patch-seq and whole-brain morphology data sets of excitatory neurons in mouse V1, unified with a multi-step classifier linking transcriptomic identity to projection targets.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-02-anatomy-primer
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (6)
claim_text
Coordinated Patch-seq and whole-brain morphology of mouse V1 excitatory neurons defines 16 integrated morpho-electric-transcriptomic (MET) types and reconstructs 300 complete morphologies; transcriptomic variation within and across MET-types plus anatomical location predicts the long-range projection target of individual neurons.
raw_fields
{
  "n": "16 MET-types; 300 reconstructed neurons",
  "doi": "10.1101/2023.11.25.568393",
  "claim": "Coordinated Patch-seq and whole-brain morphology of mouse V1 excitatory neurons defines 16 integrated morpho-electric-transcriptomic (MET) types and reconstructs 300 complete morphologies; transcriptomic variation within and across MET-types plus anatomical location predicts the long-range projection target of individual neurons.",
  "cite_key": "Sorensen2023",
  "evidence": "Coordinated Patch-seq and whole-brain morphology data sets of excitatory neurons in mouse V1, unified with a multi-step classifier linking transcriptomic identity to projection targets.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse primary visual cortex excitatory neurons, Patch-seq + complete-morphology reconstruction",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "From the Patch-seq data, we defined 16 integrated morpho-electric-transcriptomic (MET)-types; in parallel, we reconstructed the complete morphologies of 300 neurons... this variation, along with the anatomical location of the cell, can be used to predict the projection targets of individual neurons.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-pm-38168270"
]
source_span
From the Patch-seq data, we defined 16 integrated morpho-electric-transcriptomic (MET)-types; in parallel, we reconstructed the complete morphologies of 300 neurons... this variation, along with the anatomical location of the cell, can be used to predict the projection targets of individual neurons.
evidence_refs
[
  {
    "ref": "paper:paper-pm-38168270"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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