Coordinated Patch-seq and whole-brain morphology of excitatory mouse V1 neurons…

Coordinated Patch-seq and whole-brain morphology of excitatory mouse V1 neurons defines 16 integrated morpho-electrophysiological-transcriptomic types and links each transcriptomic identity to a distinct long-range cortico-cortical projection pattern, bridging single-cell transcriptomes and projectomes.

{
  "n": null,
  "doi": "10.1101/2023.11.25.568393",
  "claim": "Coordinated Patch-seq and whole-brain morphology of excitatory mouse V1 neurons defines 16 integrated morpho-electrophysiological-transcriptomic types and links each transcriptomic identity to a distinct long-range cortico-cortical projection pattern, bridging single-cell transcriptomes and projectomes.",
  "cite_key": "Sorensen2023",
  "evidence": "Coordinated Patch-seq (transcriptome + local morphology + electrophysiology) and whole-brain axon reconstruction in mouse V1 excitatory neurons.",
  "effect_size": "16 integrated MET-types in mouse V1 with mapped long-range projection patterns.",
  "text_access": "abstract_only",
  "study_system": "Mouse V1 excitatory neurons; Patch-seq + whole-brain reconstruction.",
  "argument_role": "supporting",
  "replication_status": "not_yet",
  "claim_source_sentence": "From the Patch-seq data, we defined 16 integrated morpho-electrophysiological-transcriptomic excitatory neuron types.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "To address this, we collected coordinated Patch-seq and whole brain morphology data sets of excitatory neurons in mouse visual cortex."
}

[
  "paper:paper-pm-38168270"
]

[
  {
    "ref": "paper:paper-pm-38168270"
  }
]

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}