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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- CREB Signaling in Neurodegeneration
CREB["CREB"] APOPTOSIS["APOPTOSIS"] -->|"associated with"| CREB["CREB"] Antidepressant_Treatment
Read more → - CREB Neurons
CREB["CREB Neurons"] -->|"regulates"| BDNF["BDNF"] CREB["CREB Neurons"] -->|"regulates
Read more → - CREB Protein
CREB -->|"activates"| BDNF CREB -->|"activates"| OXIDATIVE_STRESS CREB -->|"activates"| Als CREB
Read more → - CREB-independent Neuronal Survival Pathways
CREB["CREB"] APOPTOSIS["APOPTOSIS"] -->|"associated with"| CREB["CREB"] Antidepressant_Treatment
Read more → - CREB-Independent Neuronal Survival Pathways in Neurodegeneration
CREB["CREB"] APOPTOSIS["APOPTOSIS"] -->|"associated with"| CREB["CREB"] Antidepressant_Treatment
Read more →
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Related hypotheses
- Activity-Dependent Synaptic Tagging via CREB-BDNF-TrkB Signaling
CREB1 at serine 133, creating the phospho-CREB transcriptionally active form that binds to cAMP ... neuronal survival. Simultaneously, the Ras/MAPK pathway enhances CREB-mediated …
- Epigenetic Memory Reprogramming for Alzheimer's Disease
mediated overexpression 2. **CREB1 activation circuit**: CREB (cAMP response element-binding protein) is the master ... memory-related gene expression. In AD, CREB function is imp…
- Alpha-Theta Oscillation Modulation Enhances lncRNA-9969-Mediated Autophagy Through SST Interneuron-Specific ceRNA Networks
alpha-theta entrainment activates the cAMP-PKA-CREB pathway through distinct calcium dynamics mediated ... promotes sustained lncRNA-9969 transcription through prolonged CREB phos…
- Gamma-Entrained P-tau217 Biomarker Cascades Optimize lncRNA-9969 Exosome Therapy Precision in Early AD
parvalbumin (PV) interneurons. This gamma entrainment activates CREB-dependent transcription, priming PV neurons for enhanced ... lncRNA-9969` and the pathway label is `CREB-media…
- CREB-Mediated Differential CD55/CD46 Expression Creates Activity-Dependent Complement Vulnerability Maps for Synaptic Pruning
This hypothesis proposes that activity-dependent CREB signaling creates spatially distinct complement vulnerability maps ... mediated pruning. Conversely, high-activity synapses u…