No definition recorded for this entity.
Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- glutamate
GLUTAMATE["GLUTAMATE"] ALS["ALS"] -->|"associated with"| GLUTAMATE["GLUTAMATE"] style Glutamate
Read more → - Glutamate - Excitotoxicity and Neurodegeneration Biomarker
GLUTAMATE["GLUTAMATE"] ASTROCYTES["ASTROCYTES"] -->|"associated with"| GLUTAMATE["GLUTAMATE"] AMYLOID["AMYLOID
Read more → - Glutamate Transport
GLUTAMATE["GLUTAMATE"] ASTROCYTES["ASTROCYTES"] -->|"associated with"| GLUTAMATE["GLUTAMATE"] AMYLOID["AMYLOID
Read more → - Glutamate Excitotoxicity in Neurodegeneration
GLUTAMATE["GLUTAMATE"] ASTROCYTES["ASTROCYTES"] -->|"associated with"| GLUTAMATE["GLUTAMATE"] AMYLOID["AMYLOID
Read more → - Excitotoxicity in Neurodegeneration
glutamate["glutamate"] -->|"causes"| excitotoxicity["excitotoxicity"] glutamate_receptors["glutamate_receptors"] -->|"causes
Read more →
Graph neighborhood (30 nodes · 75 edges)
Click a neighbor to navigate · double-click opens in a new tab · open in full graph viewer
Related hypotheses
- AQP4-Dependent Astrocyte Swelling Exacerbates Excitotoxic Neuronal Death via Dysfunction of the Glutamate-Gln Cycle
critical nexus between astrocyte volume regulation and glutamate homeostasis in the central nervous system. AQP4 ... mechanistically disrupts the spatial organization of key gluta…
- Excitatory Neuron Vulnerability via SLC17A7 Downregulation
reads: "SLC17A7 (also known as VGLUT1, vesicular glutamate transporter 1) shows significant downregulation (log2FC ... gyrus. This reduction in the primary vesicular glutamate tra…
- Heterogeneous astrocyte activation states differentially impact neuronal survival across AD progression
mechanisms including complement-mediated synapse elimination, impaired glutamate homeostasis, blood-brain barrier (BBB) dysfunction ... susceptible to complement-mediated tagging.…
- Microglial xCT/SLC7A11 Selective Inhibition to Reduce Non-Cell-Autonomous Glutamate Toxicity
SLC3A2), represents a critical component of cellular glutamate homeostasis and oxidative stress response in amyotrophic ... exchange of extracellular cystine for intracellular glu…
- TNF-α/IL-1β-Cx43 Hemichannel Axis as Upstream Link Between SASP and Synaptic Pruning
manifold but critically include the release of glutamate into the extracellular space. Under physiological conditions ... astrocytes clear glutamate through excitatory amino acid …