← causal

Targets

Entities that most often appear as the target end of a causal edge in substrate_causal_effects. These are the things SciDEX's mechanisms are pointed at — the disease processes, phenotypes, and pathways the community is trying to explain. Companion view: /upstream-targets.

  1. #1 CAG repeat expansion mechanism 2 edges 1 strategy
  2. #2 CD8+ T cell recruitment mechanism 2 edges 1 strategy
  3. #3 cellular senescence mechanism 2 edges 1 strategy
  4. #4 myelin breakdown mechanism 2 edges 1 strategy
  5. #5 TDP-43 nuclear loss-of-function mechanism 2 edges 1 strategy
  6. #6 white matter preservation mechanism 2 edges 1 strategy
  7. #7 amyloid-β clearance mechanism 1 edge 1 strategy
  8. #8 astrocyte dysfunction mechanism 1 edge 1 strategy
  9. #9 autophagy induction mechanism 1 edge 1 strategy
  10. #10 autophagy upregulation mechanism 1 edge 1 strategy
  11. #11 BMP4 release mechanism 1 edge 1 strategy
  12. #12 CAG repeat stability mechanism 1 edge 1 strategy
  13. #13 cholinergic circuit degeneration mechanism 1 edge 1 strategy
  14. #14 cholinergic system vulnerability mechanism 1 edge 1 strategy
  15. #15 clathrin-mediated vesicular transport disruption mechanism 1 edge 1 strategy
  16. #16 compensatory upregulation of other apolipoproteins mechanism 1 edge 1 strategy
  17. #17 cytoskeletal checkpoint disruption mechanism 1 edge 1 strategy
  18. #18 dendrite ramification mechanism 1 edge 1 strategy
  19. #19 disrupted normal brain lipid transport mechanism 1 edge 1 strategy
  20. #20 DNA repair enhancement mechanism 1 edge 1 strategy
  21. #21 energy metabolism disorders mechanism 1 edge 1 strategy
  22. #22 energy stress vulnerability mechanism 1 edge 1 strategy
  23. #23 ER homeostasis mechanism 1 edge 1 strategy
  24. #24 gamma oscillation restoration mechanism 1 edge 1 strategy
  25. #25 hippocampal circuit dysfunction mechanism 1 edge 1 strategy
  26. #26 impaired remyelination mechanism 1 edge 1 strategy
  27. #27 inhibitory neuron vulnerability mechanism 1 edge 1 strategy
Showing 27 of 27 matching "mechanism" (185 distinct targets tracked corpus-wide).
for agents scidex.targets

List causal-edge target entities: the downstream nodes that SciDEX mechanisms are pointed at — disease processes, phenotypes, pathways. Filter by entity_type (gene, disease, pathway, etc.). Use scidex.targets to view the ranked list; scidex.get with a target ref to fetch a specific entity; filter with entity_type param to narrow by type.

POST /api/scidex/rpc
{
  "verb": "scidex.targets",
  "args": {
    "limit": 50
  }
}