- claim_text
Nicotinic receptor agonists had no effect on pyramidal neurons and on most types of interneurons, including parvalbumin-expressing fast spiking interneurons and somatostatin-expressing interneurons, but selectively excited a subpopulation of interneurons coexpressing the neuropeptides vasoactive intestinal peptide (VIP) and cholecystokinin.
- raw_fields
{
"n": null,
"doi": "10.1523/jneurosci.19-13-05228.1999",
"year": "1999",
"claim": "Nicotinic receptor agonists had no effect on pyramidal neurons and on most types of interneurons, including parvalbumin-expressing fast spiking interneurons and somatostatin-expressing interneurons, but selectively excited a subpopulation of interneurons coexpressing the neuropeptides vasoactive intestinal peptide (VIP) and cholecystokinin.",
"title": null,
"journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience",
"cite_key": "Porter1999",
"evidence": "Selective excitation of subtypes of neocortical interneurons by nicotinic receptors",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "rat neocortex",
"_source_cluster": "cluster_06_disinhibition_circuit",
"snowball_origin": "backward",
"replication_status": "replicated",
"_source_cluster_index": 79,
"claim_source_sentence": "Nicotinic receptor agonists had no effect on pyramidal neurons and on most types of interneurons, including parvalbumin-expressing fast spiking interneurons and somatostatin-expressing interneurons, but selectively excited a subpopulation of interneurons coexpressing the neuropeptides vasoactive intestinal peptide (VIP) and cholecystokinin.",
"replication_evidence_dois": [
"10.1038/nn.4002",
"10.1038/s41467-019-13244-9",
"10.7554/elife.57749"
],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-5f194b747ea7"
]
- source_span
Nicotinic receptor agonists had no effect on pyramidal neurons and on most types of interneurons, including parvalbumin-expressing fast spiking interneurons and somatostatin-expressing interneurons, but selectively excited a subpopulation of interneurons coexpressing the neuropeptides vasoactive intestinal peptide (VIP) and cholecystokinin.
- evidence_refs
[
{
"ref": "paper:paper-5f194b747ea7"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}