Details

scope
mouse neocortex; 5-HT3aR-BAC transgenic + ISH
section_id
section_04
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_04_evidence_package.json
effect_size
bipolar/bitufted as defining VIP morphology
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-04-morphology
source_kind
review_finding
source_path
evidence/section_04_evidence_package.json
study_system
mouse neocortex; 5-HT3aR-BAC transgenic + ISH
section_title
Morphological Diversity
evidence_summary
In situ hybridization, immunohistochemistry, fate mapping in 5HT3aR-BAC transgenic mice; biocytin fills.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-04-morphology
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_04_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
claim_text
Cortical 5-HT3aR-expressing interneurons (which encompass the entire VIP class) split into two morphological populations: a VIP+ subset with characteristic bipolar/bitufted dendritic and axonal morphology, and a VIP–/NPY+ subset with more complex dendritic arborization.
raw_fields
{
  "n": 0,
  "doi": "10.1093/cercor/bhp310",
  "claim": "Cortical 5-HT3aR-expressing interneurons (which encompass the entire VIP class) split into two morphological populations: a VIP+ subset with characteristic bipolar/bitufted dendritic and axonal morphology, and a VIP–/NPY+ subset with more complex dendritic arborization.",
  "title": null,
  "cite_key": "Vucurovic2010",
  "evidence": "In situ hybridization, immunohistochemistry, fate mapping in 5HT3aR-BAC transgenic mice; biocytin fills.",
  "effect_size": "bipolar/bitufted as defining VIP morphology",
  "text_access": "fulltext",
  "study_system": "mouse neocortex; 5-HT3aR-BAC transgenic + ISH",
  "_source_cluster": "cluster_03_morphology",
  "replication_status": "replicated",
  "_source_cluster_index": 13,
  "claim_source_sentence": "The first population was characterized by the frequent expression of the vasoactive intestinal peptide and a typical bipolar/bitufted morphology, whereas the second population expressed predominantly the neuropeptide Y and exhibited more complex dendritic arborizations.",
  "replication_evidence_dois": [
    "10.1523/jneurosci.16-08-02701.1996",
    "10.1093/cercor/bhv202"
  ],
  "effect_size_source_sentence": "VIP-positive cells are characterized by their bipolar, vertically oriented main dendrites and axon ( B 3)."
}
source_refs
[
  "paper:paper-0336a131683f"
]
source_span
The first population was characterized by the frequent expression of the vasoactive intestinal peptide and a typical bipolar/bitufted morphology, whereas the second population expressed predominantly the neuropeptide Y and exhibited more complex dendritic arborizations.
evidence_refs
[
  {
    "ref": "paper:paper-0336a131683f"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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