Details

scope
juvenile mouse S1; scRT-PCR
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
effect_size
Lhx6 0% VIP-cluster; 6% NPY-cluster
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-05-electrophysiology
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
Expression of Lhx6 was almost never detected on both VIP- and NPY-cluster (0% and 6%, respectively).
study_system
juvenile mouse S1; scRT-PCR
section_title
Intrinsic Electrophysiology
evidence_summary
scRT-PCR on patched cells (Lee 2010)
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-05-electrophysiology
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
In juvenile mouse S1, all 5-HT3aR-expressing GABAergic INs avoid expressing Lhx6 (0% in VIP-cluster, 6% in NPY-cluster) — confirming the molecular dichotomy between MGE-derived (Lhx6+) PV/SST classes and CGE-derived (5-HT3aR+/Lhx6−) VIP/Lamp5 classes at the level of single-cell transcript detection.
raw_fields
{
  "n": 53,
  "doi": "10.1093/cercor/bhp310",
  "claim": "In juvenile mouse S1, all 5-HT3aR-expressing GABAergic INs avoid expressing Lhx6 (0% in VIP-cluster, 6% in NPY-cluster) — confirming the molecular dichotomy between MGE-derived (Lhx6+) PV/SST classes and CGE-derived (5-HT3aR+/Lhx6−) VIP/Lamp5 classes at the level of single-cell transcript detection.",
  "title": null,
  "cite_key": "Vucurovic2010",
  "evidence": "scRT-PCR on patched cells (Lee 2010)",
  "effect_size": "Lhx6 0% VIP-cluster; 6% NPY-cluster",
  "text_access": "fulltext",
  "study_system": "juvenile mouse S1; scRT-PCR",
  "_source_cluster": "cluster_04_intrinsic_electrophysiology",
  "replication_status": "replicated",
  "_source_cluster_index": 87,
  "claim_source_sentence": "Expression of Lhx6 was almost never detected on both VIP- and NPY-cluster (0% and 6%, respectively).",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2018.10.009",
    "10.1002/dneu.20853"
  ],
  "effect_size_source_sentence": "Expression of Lhx6 was almost never detected on both VIP- and NPY-cluster (0% and 6%, respectively)."
}
source_refs
[
  "paper:paper-0336a131683f"
]
evidence_refs
[
  {
    "ref": "paper:paper-0336a131683f"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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