- raw_fields
{
"n": null,
"doi": "10.1016/j.crmeth.2025.101180",
"claim": "A real-time all-optical interface enables closed-loop holographic perturbation of identified mouse cortical ensembles during behavior, allowing online readout-triggered stimulation.",
"cite_key": "Zhang2025a",
"evidence": "Proof-of-principle closed-loop experiments in awake behaving mice.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "awake behaving mouse cortex",
"argument_role": "supporting",
"replication_status": "single_study",
"claim_source_sentence": "The system integrates a state-of-the-art calcium imaging analysis package that achieves rapid online activity readout from two-photon calcium imaging, a custom hologram generation program that targets two-photon optogenetic stimulation of specific neuronal ensembles, and software modules that automate essential steps in running complex all-optical experiments.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-e5c1698c5067"
]
- source_span
The system integrates a state-of-the-art calcium imaging analysis package that achieves rapid online activity readout from two-photon calcium imaging, a custom hologram generation program that targets two-photon optogenetic stimulation of specific neuronal ensembles, and software modules that automate essential steps in running complex all-optical experiments.
- evidence_refs
[
{
"ref": "paper:paper-e5c1698c5067"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}