Details
- scope
- mouse primary visual cortex (V1) engram
- claim_text
- In mouse V1, visually-cued engram neurons tagged by TRAP are selectively reactivated during post-conditioning sleep, and optogenetic inhibition of these neurons during sleep disrupts consolidation of the fear memory.
- section_id
- section_11
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-11-pattern-completion
- source_kind
- review_finding
- source_path
- evidence/section_11_evidence_package.json
- source_span
- Optogenetic inhibition of the engram population during post-conditioning sleep disrupts consolidation of fear memory.
- study_system
- mouse primary visual cortex (V1) engram
- section_title
- 11. Physiological signature III — pattern completion, replay, and sequence generation as recurrent-circuit read-outs in mouse cortex
- evidence_summary
- TRAP-tagged V1 engram + optogenetic inhibition during sleep + behavioral fear assays in mice.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- within_lab_replication
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-11-pattern-completion
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1038/s41467-021-21471-2", "claim": "In mouse V1, visually-cued engram neurons tagged by TRAP are selectively reactivated during post-conditioning sleep, and optogenetic inhibition of these neurons during sleep disrupts consolidation of the fear memory.", "cite_key": "Clawson2021", "evidence": "TRAP-tagged V1 engram + optogenetic inhibition during sleep + behavioral fear assays in mice.", "effect_size": null, "text_access": "abstract_only", "study_system": "mouse primary visual cortex (V1) engram", "argument_role": "supporting", "replication_status": "within_lab_replication", "claim_source_sentence": "Optogenetic inhibition of the engram population during post-conditioning sleep disrupts consolidation of fear memory.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [ "10.1126/sciadv.adu9800", "10.1073/pnas.1818432116" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-db04b23b3693" ]
- evidence_refs
[ { "ref": "paper:paper-db04b23b3693" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }