Details

scope
mouse barrel cortex in vivo
claim_text
An all-optical platform combining two-photon optogenetic activation of red-shifted opsin with simultaneous two-photon calcium imaging enables single-cell-resolution interrogation of functionally defined ensembles in mouse cortex in vivo.
section_id
section_11
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-11-pattern-completion
source_kind
review_finding
source_path
evidence/section_11_evidence_package.json
study_system
mouse barrel cortex in vivo
section_title
11. Physiological signature III — pattern completion, replay, and sequence generation as recurrent-circuit read-outs in mouse cortex
evidence_summary
All-optical SLM-based 2p imaging+activation in mouse barrel cortex.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-11-pattern-completion
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
raw_fields
{
  "n": null,
  "doi": "10.1038/nmeth.3217",
  "claim": "An all-optical platform combining two-photon optogenetic activation of red-shifted opsin with simultaneous two-photon calcium imaging enables single-cell-resolution interrogation of functionally defined ensembles in mouse cortex in vivo.",
  "cite_key": "Packer2015",
  "evidence": "All-optical SLM-based 2p imaging+activation in mouse barrel cortex.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse barrel cortex in vivo",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "A spatial light modulator allows tens of user-selected neurons to be targeted for spatiotemporally precise concurrent optogenetic activation, while simultaneous fast calcium imaging provides high-resolution network-wide readout of the manipulation with negligible optical cross-talk.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1126/science.aaf7560",
    "10.7554/eLife.58889"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-da9fd53ac71d"
]
source_span
A spatial light modulator allows tens of user-selected neurons to be targeted for spatiotemporally precise concurrent optogenetic activation, while simultaneous fast calcium imaging provides high-resolution network-wide readout of the manipulation with negligible optical cross-talk.
evidence_refs
[
  {
    "ref": "paper:paper-da9fd53ac71d"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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