Details

scope
awake mouse V1, visual discrimination behavior
claim_text
Holographic activation of two pattern-completion neurons in mouse V1 can recall a task-relevant ensemble and improve or evoke the corresponding behavioral choice in absence of visual input.
section_id
section_11
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json
effect_size
two pattern completion neurons sufficient
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-11-pattern-completion
source_kind
review_finding
source_path
evidence/section_11_evidence_package.json
source_span
Finally, in absence of visual stimuli, optogenetic activation of two pattern completion neurons could trigger behaviorally relevant ensembles and correct behavioral responses.
study_system
awake mouse V1, visual discrimination behavior
section_title
11. Physiological signature III — pattern completion, replay, and sequence generation as recurrent-circuit read-outs in mouse cortex
evidence_summary
Two-photon holographic optogenetics in mouse V1 during a visual go/no-go task; activation of pattern-completion neurons recalled whole ensemble and biased behavior.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
within_lab_replication
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-11-pattern-completion
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.cell.2019.05.045",
  "claim": "Holographic activation of two pattern-completion neurons in mouse V1 can recall a task-relevant ensemble and improve or evoke the corresponding behavioral choice in absence of visual input.",
  "cite_key": "CarrilloReid2019",
  "evidence": "Two-photon holographic optogenetics in mouse V1 during a visual go/no-go task; activation of pattern-completion neurons recalled whole ensemble and biased behavior.",
  "effect_size": "two pattern completion neurons sufficient",
  "text_access": "abstract_only",
  "study_system": "awake mouse V1, visual discrimination behavior",
  "argument_role": "supporting",
  "replication_status": "within_lab_replication",
  "claim_source_sentence": "Finally, in absence of visual stimuli, optogenetic activation of two pattern completion neurons could trigger behaviorally relevant ensembles and correct behavioral responses.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1126/science.aaf7560"
  ],
  "effect_size_source_sentence": "activation of only two pattern completion neurons from behaviorally relevant ensembles improved performance, by reliably recalling the whole ensemble."
}
source_refs
[
  "paper:paper-e37e0b6bad65"
]
evidence_refs
[
  {
    "ref": "paper:paper-e37e0b6bad65"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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