- claim_text
In a model designed for spatial working memory, stimulus tuning of persistent activity arises from the concerted action of widespread inhibition mediated by perisoma-targeting (parvalbumin-containing) interneurons and localized disinhibition of pyramidal cells via interneuron-targeting (calretinin-containing) interneurons.
- raw_fields
{
"n": null,
"doi": "10.1073/pnas.0305337101",
"year": "2004",
"claim": "In a model designed for spatial working memory, stimulus tuning of persistent activity arises from the concerted action of widespread inhibition mediated by perisoma-targeting (parvalbumin-containing) interneurons and localized disinhibition of pyramidal cells via interneuron-targeting (calretinin-containing) interneurons.",
"title": null,
"journal": "Proceedings of the National Academy of Sciences of the United States of America",
"cite_key": "Wang2004a",
"evidence": "Division of labor among distinct subtypes of inhibitory neurons in a cortical microcircuit of working memory",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "mammal PFC",
"_source_cluster": "cluster_06_disinhibition_circuit",
"snowball_origin": "backward",
"replication_status": "replication_unknown",
"_source_cluster_index": 74,
"claim_source_sentence": "In a model designed for spatial working memory, stimulus tuning of persistent activity arises from the concerted action of widespread inhibition mediated by perisoma-targeting (parvalbumin-containing) interneurons and localized disinhibition of pyramidal cells via interneuron-targeting (calretinin-containing) interneurons.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-4ced38bcaa48"
]
- source_span
In a model designed for spatial working memory, stimulus tuning of persistent activity arises from the concerted action of widespread inhibition mediated by perisoma-targeting (parvalbumin-containing) interneurons and localized disinhibition of pyramidal cells via interneuron-targeting (calretinin-containing) interneurons.
- evidence_refs
[
{
"ref": "paper:paper-4ced38bcaa48"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}