Layer-1 VIP interneurons in both human and mouse exhibit characteristic descend…

Details

scope: human neurosurgical tissue + mouse VISp; Patch-seq
claim_text: Layer-1 VIP interneurons in both human and mouse exhibit characteristic descending axon collaterals, but mouse L1-VIP cells show greater morphological variability than the more uniform human L1-VIP TSPAN12 type.
section_id: section_04
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_04_evidence_package.json
effect_size: cross-species morphological convergence with quantitative divergence
review_repo: ComputationalReviewVIP
section_ref: wiki_page:computationalreviewvip-04-morphology
source_kind: review_finding
source_path: evidence/section_04_evidence_package.json
source_span: Mouse VIP cells had descending axon branches as in human VIP cells, but with greater variability of structure.
study_system: human neurosurgical tissue + mouse VISp; Patch-seq
section_title: Morphological Diversity
evidence_summary: Cross-species Patch-seq + biocytin reconstruction of L1 interneurons from human neurosurgical tissue and mouse VISp.
review_bundle_ref: analysis_bundle:ab-2ce40c33e827
replication_status: needs_replication
review_package_ref: analysis_bundle:ab-2ce40c33e827
source_artifact_ref: wiki_page:computationalreviewvip-04-morphology
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_04_evidence_package.json
commit_sha: 95e761177f7d2ec565983d3307c14ec238f9677c
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1126/science.adf0805",
  "claim": "Layer-1 VIP interneurons in both human and mouse exhibit characteristic descending axon collaterals, but mouse L1-VIP cells show greater morphological variability than the more uniform human L1-VIP TSPAN12 type.",
  "title": null,
  "cite_key": "Chartrand2023",
  "evidence": "Cross-species Patch-seq + biocytin reconstruction of L1 interneurons from human neurosurgical tissue and mouse VISp.",
  "effect_size": "cross-species morphological convergence with quantitative divergence",
  "text_access": "fulltext",
  "study_system": "human neurosurgical tissue + mouse VISp; Patch-seq",
  "_source_cluster": "cluster_03_morphology",
  "replication_status": "needs_replication",
  "_source_cluster_index": 23,
  "claim_source_sentence": "Mouse VIP cells had descending axon branches as in human VIP cells, but with greater variability of structure.",
  "replication_evidence_dois": [
    "10.1126/science.adf6484"
  ],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-86dac47be132"
]

evidence_refs

[
  {
    "ref": "paper:paper-86dac47be132"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

Layer-1 VIP interneurons in both human and mouse exhibit characteristic descend…

Details

Replication

Discussion