- claim_text
VIP interneurons in mouse S1 cortex preferentially inhibit somatostatin (SST)-expressing interneurons, generating dendrite-targeted disinhibition during whisking — consistent with a disinhibition role implied by VIP morphology being concentrated near interneuron somata in L2/3.
- raw_fields
{
"n": 0,
"doi": "10.1038/nn.3544",
"claim": "VIP interneurons in mouse S1 cortex preferentially inhibit somatostatin (SST)-expressing interneurons, generating dendrite-targeted disinhibition during whisking — consistent with a disinhibition role implied by VIP morphology being concentrated near interneuron somata in L2/3.",
"title": null,
"cite_key": "Lee2013",
"evidence": "Channelrhodopsin-assisted circuit mapping (CRACM) of vM1→S1 axons targeting different S1 interneuron classes; in vivo imaging.",
"effect_size": "VIP→SST disinhibitory pathway",
"text_access": "fulltext",
"study_system": "mouse barrel cortex; CRACM + 2P imaging",
"_source_cluster": "cluster_03_morphology",
"replication_status": "replicated",
"_source_cluster_index": 10,
"claim_source_sentence": "These VIP interneurons preferentially inhibited somatostatin-expressing interneurons, neurons that target the distal dendrites of pyramidal cells.",
"replication_evidence_dois": [
"10.1093/cercor/bhx220",
"10.1093/cercor/bhv202"
],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-f02f24cb44ff"
]
- evidence_refs
[
{
"ref": "paper:paper-f02f24cb44ff"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}