Details

scope
vip-interneurons
claim_text
Optogenetic VIP activation in auditory cortex disinhibits pyramidal cells and enhances cortical responses, demonstrating a canonical disinhibitory motif conserved across cortex.
section_id
section_09
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_09_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-09-cross-areas
source_kind
review_finding
source_path
evidence/section_09_evidence_package.json
source_span
By combining optogenetic activation with single cell recordings, we examined the functional role of VIP interneurons in awake mice, and investigated the underlying circuit mechanisms in vitro in auditory and medial prefrontal cortices.
section_title
VIP Interneurons Across Brain Regions
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
unevaluated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-09-cross-areas
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_09_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1038/nature12676",
  "year": "2013",
  "claim": "Optogenetic VIP activation in auditory cortex disinhibits pyramidal cells and enhances cortical responses, demonstrating a canonical disinhibitory motif conserved across cortex.",
  "title": null,
  "region": "auditory cortex / mPFC",
  "cite_key": "Pi2013",
  "effect_size": null,
  "text_access": "fulltext",
  "conflict_flag": false,
  "fig_table_ref": "Fig.2-3",
  "_source_cluster": "cluster_08_brain_regions",
  "evidence_gap_flag": false,
  "unreplicated_flag": false,
  "replication_status": null,
  "_source_cluster_index": 2,
  "claim_source_sentence": "By combining optogenetic activation with single cell recordings, we examined the functional role of VIP interneurons in awake mice, and investigated the underlying circuit mechanisms in vitro in auditory and medial prefrontal cortices."
}
source_refs
[
  "paper:paper-065a0eae69a5"
]
evidence_refs
[
  {
    "ref": "paper:paper-065a0eae69a5"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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