Details
- scope
- Mouse auditory cortex in vivo, fear-conditioning, optogenetics + paired recordings (VIP-Cre)
- section_id
- section_06
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-06-synaptic-properties
- source_kind
- review_finding
- source_path
- evidence/section_06_evidence_package.json
- source_span
- VIP-expressing interneurons in auditory cortex are activated by reinforcement signals and mediate disinhibition of pyramidal cells by inhibiting other interneurons.
- study_system
- Mouse auditory cortex in vivo, fear-conditioning, optogenetics + paired recordings (VIP-Cre)
- section_title
- Synaptic Properties and Connectivity
- evidence_summary
- VIP-expressing interneurons in auditory cortex are activated by reinforcement signals and mediate disinhibition of pyramidal cells by inhibiting other interneurons.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-06-synaptic-properties
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- claim_text
In auditory cortex, optogenetic activation of VIP interneurons disinhibits pyramidal cells by mainly silencing SST and PV interneurons; reinforcement-related basal forebrain inputs recruit this VIP-mediated disinhibitory motif during behavior.
- raw_fields
{ "n": null, "doi": "10.1038/nature12676", "claim": "In auditory cortex, optogenetic activation of VIP interneurons disinhibits pyramidal cells by mainly silencing SST and PV interneurons; reinforcement-related basal forebrain inputs recruit this VIP-mediated disinhibitory motif during behavior.", "title": null, "cite_key": "Pi2013", "evidence": "VIP-expressing interneurons in auditory cortex are activated by reinforcement signals and mediate disinhibition of pyramidal cells by inhibiting other interneurons.", "effect_size": null, "text_access": "abstract_only", "study_system": "Mouse auditory cortex in vivo, fear-conditioning, optogenetics + paired recordings (VIP-Cre)", "_source_cluster": "cluster_05_synaptic_connectivity", "replication_status": "independently_replicated", "_source_cluster_index": 1, "claim_source_sentence": "VIP-expressing interneurons in auditory cortex are activated by reinforcement signals and mediate disinhibition of pyramidal cells by inhibiting other interneurons.", "replication_evidence_dois": [ "10.1038/nn.3446", "10.1038/nn.3544", "10.1126/science.1254126" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-065a0eae69a5" ]
- evidence_refs
[ { "ref": "paper:paper-065a0eae69a5" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }