Details
- scope
- mammal PFC/mPFC/frontal cortex
- claim_text
- Regular cortical VIP interneurons disinhibit local pyramidal neurons by selectively inhibiting somatostatin (SST) and parvalbumin (PV)-expressing interneurons 26 , 28 , 30 , 31 , 50 .
- section_id
- section_07
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-07-disinhibition-framework
- source_kind
- review_finding
- source_path
- evidence/section_07_evidence_package.json
- source_span
- Regular cortical VIP interneurons disinhibit local pyramidal neurons by selectively inhibiting somatostatin (SST) and parvalbumin (PV)-expressing interneurons 26 , 28 , 30 , 31 , 50 .
- study_system
- mammal PFC/mPFC/frontal cortex
- section_title
- Local Circuit Motifs and the Disinhibition Framework
- evidence_summary
- Prefrontal cortical ChAT-VIP interneurons provide local excitation by cholinergic synaptic transmission and control attention
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-07-disinhibition-framework
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1038/s41467-019-13244-9", "year": "2019", "claim": "Regular cortical VIP interneurons disinhibit local pyramidal neurons by selectively inhibiting somatostatin (SST) and parvalbumin (PV)-expressing interneurons 26 , 28 , 30 , 31 , 50 .", "title": null, "journal": "Nature communications", "cite_key": "Obermayer2019", "evidence": "Prefrontal cortical ChAT-VIP interneurons provide local excitation by cholinergic synaptic transmission and control attention", "effect_size": null, "text_access": "fulltext", "first_author": "Obermayer", "study_system": "mammal PFC/mPFC/frontal cortex", "_source_cluster": "cluster_06_disinhibition_circuit", "author_list_short": "Obermayer, Luchicchi, Heistek", "replication_status": "replicated", "_source_cluster_index": 39, "claim_source_sentence": "Regular cortical VIP interneurons disinhibit local pyramidal neurons by selectively inhibiting somatostatin (SST) and parvalbumin (PV)-expressing interneurons 26 , 28 , 30 , 31 , 50 .", "replication_evidence_dois": [ "10.1038/nn.4002", "10.1038/nm.4274" ], "effect_size_source_sentence": "A fraction (10–20%) of postsynaptic neurons that received cholinergic input from ChAT-VIP interneurons also received GABAergic input from these neurons." }- source_refs
[ "paper:paper-d66bdd18df1c" ]
- evidence_refs
[ { "ref": "paper:paper-d66bdd18df1c" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }