Details
- scope
- mouse prefrontal cortex to ventral striatum circuit
- claim_text
- Prefrontal PV interneurons regulate social reward by modulating PFC-ventral striatum output; this circuit is disrupted in ASD and schizophrenia models
- section_id
- section_09_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_09_evidence_package.json
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-09
- source_kind
- review_finding
- source_path
- evidence/section_09_evidence_package.json
- source_span
- Here, we synthesize existing findings and propose a novel mechanism in which prefrontal parvalbumin (PV) interneurons regulate social reward by modulating PFC-vSTR output.
- study_system
- mouse prefrontal cortex to ventral striatum circuit
- section_title
- Brain Region and Layer Context: Beyond Primary Sensory Cortex
- evidence_summary
- Prefrontal PV interneurons regulate social reward by modulating PFC-ventral striatum output; this circuit is disrupted in ASD and schizophrenia models
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-09
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_09_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1016/j.pneurobio.2025.102834", "claim": "Prefrontal PV interneurons regulate social reward by modulating PFC-ventral striatum output; this circuit is disrupted in ASD and schizophrenia models", "evidence": "Prefrontal PV interneurons regulate social reward by modulating PFC-ventral striatum output; this circuit is disrupted in ASD and schizophrenia models", "effect_size": null, "text_access": "fulltext", "study_system": "mouse prefrontal cortex to ventral striatum circuit", "replication_status": "replication_unknown", "claim_source_sentence": "Here, we synthesize existing findings and propose a novel mechanism in which prefrontal parvalbumin (PV) interneurons regulate social reward by modulating PFC-vSTR output.", "replication_evidence_dois": [], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-aaa9b78f6a75" ]
- evidence_refs
[ { "ref": "paper:paper-aaa9b78f6a75" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }