- claim_text
VIP inhibitory interneurons in V1 receive cortical top-down and neuromodulatory inputs, and can disinhibit local principal cells through prominent inhibitory connections onto somatostatin-expressing (SOM) inhibitory interneurons 24 – 28 , providing a circuit for top-down gain modulation of sensory responses 29 , 30 .
- raw_fields
{
"n": null,
"doi": "10.1038/s41586-024-07851-w",
"year": "2024",
"claim": "VIP inhibitory interneurons in V1 receive cortical top-down and neuromodulatory inputs, and can disinhibit local principal cells through prominent inhibitory connections onto somatostatin-expressing (SOM) inhibitory interneurons 24 – 28 , providing a circuit for top-down gain modulation of sensory responses 29 , 30 .",
"title": null,
"journal": "Nature",
"cite_key": "Furutachi2024",
"evidence": "Cooperative thalamocortical circuit mechanism for sensory prediction errors",
"effect_size": "10% of",
"text_access": "fulltext",
"study_system": "mouse V1",
"_source_cluster": "cluster_06_disinhibition_circuit",
"replication_status": "replication_unknown",
"_source_cluster_index": 52,
"claim_source_sentence": "VIP inhibitory interneurons in V1 receive cortical top-down and neuromodulatory inputs, and can disinhibit local principal cells through prominent inhibitory connections onto somatostatin-expressing (SOM) inhibitory interneurons 24 – 28 , providing a circuit for top-down gain modulation of sensory responses 29 , 30 .",
"replication_evidence_dois": [],
"effect_size_source_sentence": "On day six (C session), the identity of the stimulus at the fourth position changed in a subset of trials: a novel grating stimulus C was first shown instead of the second grating stimulus B in 10% of trials (block 1, 160 trials in total; Fig."
}- source_refs
[
"paper:paper-41aa556ea384"
]
- source_span
VIP inhibitory interneurons in V1 receive cortical top-down and neuromodulatory inputs, and can disinhibit local principal cells through prominent inhibitory connections onto somatostatin-expressing (SOM) inhibitory interneurons 24 – 28 , providing a circuit for top-down gain modulation of sensory responses 29 , 30 .
- evidence_refs
[
{
"ref": "paper:paper-41aa556ea384"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}