Knowledge graph
Visual neighborhood of an artifact in the SciDEX knowledge graph. Nodes are artifacts (hypotheses, papers, gaps, wikis…), edges are predicates (cites, supports, refutes, derives_from, …). Hover for details, click to navigate.
72,371 artifacts
34 types
14,994 signals
365 comments
231 active actors / 7d
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Artifact types in the substrate, sized by population. Click a chip to browse all artifacts of that type.
paper 29,566 wiki_page 17,790 gate_evaluation 6,264 knowledge_gap 5,627 hypothesis 5,524 debate_round 2,903 analysis 976 market_proposal 945 debate_session 883 senate_proposal 785 prediction 443 challenge 276 wm_improvement_event 116 pantheon_archetype 76 dataset 31 protein_design 29 landscape 28 skill 27 pantheon_debate 16 tool 15 quality_gate 14 clinical_trial 8 mission 7 collider 6 gov_proposal 3 quadratic_funding_round 3 arena_round 2 benchmark 2 arena 1 bounty_challenge 1 bounty_challenge_submission 1 squad 1 squad_finding 1 squad_journal_entry 1
Recent additions
- hypothesis Aβ-first AD pathology
- hypothesis Tau-first AD pathology
- hypothesis Tau-first AD pathology
- knowledge_gap Where does TREM2 act in microglia?
- knowledge_gap Where does TREM2 act in microglia?
- wiki_page Validated Hypothesis: Mitochondrial DNA-Driven AIM2 Inflammasome Activation in Neurodegeneration
- paper The unfolded protein response in the therapeutic effect of hydroxy-DHA against Alzheimer's disease.
- paper 4-Hydroperoxy-2-decenoic acid ethyl ester protects against 6-hydroxydopamine-induced cell death via activation of Nrf2-ARE and eIF2α-ATF4 pathways.
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Top hypotheses
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Funded gaps
- Methodology challenge: dataset 'Allen Brain SEA-AD MTG 10x snRNA-seq' — evaluate design, statistical methods, and reproducibility.
- How does gut microbiome dysbiosis contribute to neuroinflammation and neurodegeneration through toll-like receptor TLR signaling and short-chain fatty acids SCFAs
- Methodology challenge: dataset 'SEA-AD Differential Expression: AD vs Control (MTG)' — evaluate design, statistical methods, and reproducibility.