Details

scope
mouse whole-brain transsynaptic tracing
section_id
section_07
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-07
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
source_span
In the neocortex, sensorimotor regions contain the most labeled neurons, but we find higher densities in associative areas, including orbital, anterior cingulate, prelimbic, and infralimbic cortex.
study_system
mouse whole-brain transsynaptic tracing
section_title
Parallel Loop Channels: Motor, Limbic, Associative, and Beyond the Classic Three
evidence_summary
Whole-brain transsynaptic tracing in mouse demonstrates that single cerebellar areas link to diverse forebrain targets including limbic and associative cortices, supporting homologous parallel cerebellar networks.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-07
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
claim_text
Transsynaptic tracing reveals that descending paths from cerebellum originate predominantly from somatomotor cortex, but in the neocortex sensorimotor regions show the most labeled neurons while higher densities are found in associative orbital, anterior cingulate, prelimbic, and infralimbic cortex.
raw_fields
{
  "n": 23,
  "doi": "10.1016/j.celrep.2021.109721",
  "claim": "Transsynaptic tracing reveals that descending paths from cerebellum originate predominantly from somatomotor cortex, but in the neocortex sensorimotor regions show the most labeled neurons while higher densities are found in associative orbital, anterior cingulate, prelimbic, and infralimbic cortex.",
  "cite_key": "Pisano2021",
  "evidence": "Whole-brain transsynaptic tracing in mouse demonstrates that single cerebellar areas link to diverse forebrain targets including limbic and associative cortices, supporting homologous parallel cerebellar networks.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "mouse whole-brain transsynaptic tracing",
  "source_cluster_id": "cluster_06",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "In the neocortex, sensorimotor regions contain the most labeled neurons, but we find higher densities in associative areas, including orbital, anterior cingulate, prelimbic, and infralimbic cortex.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-435bc71806c9"
]
evidence_refs
[
  {
    "ref": "paper:paper-435bc71806c9"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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