- claim_text
Five parallel frontal–subcortical circuits—originating from supplementary motor area, frontal eye field, dorsolateral prefrontal, lateral orbitofrontal, and anterior cingulate cortex—link frontal cortex through striatum, basal ganglia and thalamus, with characteristic syndromes when each is lesioned.
- raw_fields
{
"n": 0,
"doi": "10.1016/s0022-3999(02)00428-2",
"claim": "Five parallel frontal–subcortical circuits—originating from supplementary motor area, frontal eye field, dorsolateral prefrontal, lateral orbitofrontal, and anterior cingulate cortex—link frontal cortex through striatum, basal ganglia and thalamus, with characteristic syndromes when each is lesioned.",
"cite_key": "Tekin2002",
"evidence": "Synthesis of the Alexander/DeLong five-circuit schema with clinical correlation: dorsolateral lesions → executive dysfunction; orbitofrontal lesions → disinhibition; anterior cingulate lesions → apathy.",
"effect_size": "",
"text_access": "abstract_only",
"study_system": "human / clinical neurology (review)",
"source_cluster_id": "cluster_06",
"replication_status": "independently_replicated",
"claim_source_sentence": "Five parallel frontal-subcortical circuits link the specific areas of the frontal cortex to the striatum, basal ganglia and thalamus.",
"replication_evidence_dois": [
"10.1038/npp.2009.129",
"10.1007/s00429-016-1250-9"
],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-b0af7a0183ae"
]
- evidence_refs
[
{
"ref": "paper:paper-b0af7a0183ae"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}