Details

scope
mouse cortex (see paper for region/cell-type detail)
section_id
section_11
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-11-pattern-completion
source_kind
review_finding
source_path
evidence/section_11_evidence_package.json
source_span
Here we use RNA-Seq to identify genes whose expression is enriched in activated cortical ensembles labeled during associative fear learning.
study_system
mouse cortex (see paper for region/cell-type detail)
section_title
11. Physiological signature III — pattern completion, replay, and sequence generation as recurrent-circuit read-outs in mouse cortex
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single_study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-11-pattern-completion
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (6)
claim_text
RNA sequencing from neural ensembles activated during fear conditioning in the mouse temporal association cortex. Here we use RNA-Seq to identify genes whose expression is enriched in activated cortical ensembles labeled during associative fear learning.
raw_fields
{
  "n": null,
  "doi": "10.1038/srep31753",
  "claim": "RNA sequencing from neural ensembles activated during fear conditioning in the mouse temporal association cortex. Here we use RNA-Seq to identify genes whose expression is enriched in activated cortical ensembles labeled during associative fear learning.",
  "cite_key": "Cho2016",
  "evidence": "RNA sequencing from neural ensembles activated during fear conditioning in the mouse temporal association cortex. — The stable formation of remote fear memories is thought to require neuronal gene induction in cortical ensembles that are activated during learning. However, the set of genes expressed specifically in these activated ensembles is not known; knowledge of such transcriptional profiles may offer insigh",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse cortex (see paper for region/cell-type detail)",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "Here we use RNA-Seq to identify genes whose expression is enriched in activated cortical ensembles labeled during associative fear learning.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-27557751"
]
evidence_refs
[
  {
    "ref": "paper:paper-27557751"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}
evidence_summary
RNA sequencing from neural ensembles activated during fear conditioning in the mouse temporal association cortex. — The stable formation of remote fear memories is thought to require neuronal gene induction in cortical ensembles that are activated during learning. However, the set of genes expressed specifically in these activated ensembles is not known; knowledge of such transcriptional profiles may offer insigh

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