A multilayer visual microcircuit model produces switching dynamics between rate…

{
  "n": null,
  "id": "cluster_11_finding_09",
  "doi": "10.7554/elife.77594",
  "pmid": "35994330",
  "year": "2022",
  "claim": "A multilayer visual microcircuit model produces switching dynamics between rate-coded and oscillatory regimes via VIP-mediated disinhibition of SST, supporting context-dependent gain modulation.",
  "pmcid": "PMC9395191",
  "title": "Rate and oscillatory switching dynamics of a multilayer visual microcircuit model.",
  "authors": "Hahn G, Kumar A, Schmidt H, Knösche TR, Deco G.",
  "journal": "eLife",
  "cite_key": "Hahn2022",
  "evidence": "Bifurcation analysis in disinhibition strength reveals regime switches.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "multilayer cortical microcircuit rate model (incl. VIP, SST, PV)",
  "_source_cluster": "cluster_11_computational_models",
  "replication_status": "replicated_independent",
  "_source_cluster_index": 8,
  "claim_source_sentence": "The underlying switching mechanics are realized by the interactions among the three interneuron types (PV, SST, and VIP), which compete for inhibitory influence on pyramidal cells.",
  "replication_evidence_dois": [
    "10.1073/pnas.2504164122",
    "10.1371/journal.pcbi.1013469",
    "10.1371/journal.pcbi.1012036",
    "10.1093/cercor/bhae378",
    "10.1007/s00422-021-00894-6"
  ],
  "effect_size_source_sentence": null
}

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]

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  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
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