Details
- scope
- biologically detailed spiking V1 cortical column model (Allen Institute parameters)
- claim_text
- A V1 cortical column spiking model demonstrates that the E–SST–VIP triangle produces dynamics richer than a classical disinhibitory pathway, with SST responses depending on layer-specific feedforward vs. feedback drive.
- section_id
- section_12
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-12-computational-models
- source_kind
- review_finding
- source_path
- evidence/section_12_evidence_package.json
- source_span
- Our model suggests that the dynamics between pyramidal, SST and VIP cells are more complex that what is usually assumed when envisaging a classical disinhibitory pathway [ 48 ].
- study_system
- biologically detailed spiking V1 cortical column model (Allen Institute parameters)
- section_title
- Computational Models of VIP Circuit Function
- evidence_summary
- Model predicts opposite SST responses in L4 to perturbing pyramidal cells under feedforward vs feedback states.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated_independent
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-12-computational-models
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
- raw_fields
{ "n": null, "id": "cluster_11_finding_05", "doi": "10.1371/journal.pcbi.1012036", "pmid": "40267074", "year": "2025", "claim": "A V1 cortical column spiking model demonstrates that the E–SST–VIP triangle produces dynamics richer than a classical disinhibitory pathway, with SST responses depending on layer-specific feedforward vs. feedback drive.", "pmcid": "PMC12017539", "title": "Cell-type-specific firing patterns in a V1 cortical column model depend on feedforward and feedback-driven states.", "authors": "Moreni G, Dorcioman RA, Pennartz CMA, Mejias JF.", "journal": "PLoS computational biology", "cite_key": "Moreni2025a", "evidence": "Model predicts opposite SST responses in L4 to perturbing pyramidal cells under feedforward vs feedback states.", "effect_size": null, "text_access": "fulltext", "study_system": "biologically detailed spiking V1 cortical column model (Allen Institute parameters)", "_source_cluster": "cluster_11_computational_models", "replication_status": "replicated_independent", "_source_cluster_index": 4, "claim_source_sentence": "Our model suggests that the dynamics between pyramidal, SST and VIP cells are more complex that what is usually assumed when envisaging a classical disinhibitory pathway [ 48 ].", "replication_evidence_dois": [ "10.1073/pnas.2504164122", "10.1371/journal.pcbi.1013469", "10.1093/cercor/bhae378", "10.1007/s00422-021-00894-6", "10.7554/elife.77594" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-a3a99e8d30d7" ]
- evidence_refs
[ { "ref": "paper:paper-a3a99e8d30d7" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }