A four-interneuron-type cortical microcircuit model implements predictive codin…

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  "doi": "10.1371/journal.pcbi.1013469",
  "pmid": "40929236",
  "year": "2025",
  "claim": "A four-interneuron-type cortical microcircuit model implements predictive coding via VIP→SST→excitatory disinhibition during prediction-error computation, generating distinct oscillatory regimes for matched vs. mismatched inputs.",
  "pmcid": "PMC12443261",
  "title": "Cortical networks with multiple interneuron types generate oscillatory patterns during predictive coding.",
  "authors": "Lee K, Pennartz CMA, Mejias JF.",
  "journal": "PLoS computational biology",
  "cite_key": "Lee2025",
  "evidence": "Model embeds VIP→SST disinhibitory motif within Bastos-style PC architecture; connection strengths align with empirical Pfeffer-style data.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "rate-based predictive coding microcircuit model with E, PV, SST, VIP populations",
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  "replication_status": "replicated_independent",
  "_source_cluster_index": 1,
  "claim_source_sentence": "For example, our model’s strong excitatory connections between L2/3 excitatory and PV cells and the disinhibitory circuit from VIP to SST to excitatory cells in prediction error microcircuits align with the high connection probabilities and strengths reported in [ 59 ].",
  "replication_evidence_dois": [
    "10.1073/pnas.2504164122",
    "10.1371/journal.pcbi.1012036",
    "10.1093/cercor/bhae378",
    "10.1007/s00422-021-00894-6",
    "10.7554/elife.77594"
  ],
  "effect_size_source_sentence": null
}

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  "paper:paper-193dfb3c1e40"
]

For example, our model’s strong excitatory connections between L2/3 excitatory and PV cells and the disinhibitory circuit from VIP to SST to excitatory cells in prediction error microcircuits align with the high connection probabilities and strengths reported in [ 59 ].

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