An E-PV-SST-VIP microcircuit model captures gain modulation, decision-making, a…

{
  "n": null,
  "id": "cluster_11_finding_14",
  "doi": "10.1093/cercor/bhac355",
  "pmid": "36130096",
  "year": "2023",
  "claim": "An E-PV-SST-VIP microcircuit model captures gain modulation, decision-making, and prediction-error roles attributed to disinhibition, with VIP→SST→E identified as the principal disinhibitory motif.",
  "pmcid": "PMC10110453",
  "title": "A microcircuit model involving parvalbumin, somatostatin, and vasoactive intestinal polypeptide inhibitory interneurons for the modulation of neuronal oscillation during visual processing.",
  "authors": "Wagatsuma N, Nobukawa S, Fukai T.",
  "journal": "Cerebral cortex (New York, N.Y. : 1991)",
  "cite_key": "Wagatsuma2023",
  "evidence": "Linear stability and simulation across tasks links VIP recruitment to flexible computation.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "rate-model cortical microcircuit",
  "_source_cluster": "cluster_11_computational_models",
  "replication_status": "replicated_independent",
  "_source_cluster_index": 13,
  "claim_source_sentence": "Roles of synaptic strengths and delays from VIP to SOM interneurons for attentional modulation in layers 2/3 of the V1 In our model, attentional modulation in the cortical microcircuit occurred via disinhibition, which was based on connections from VIP to SOM interneurons ( Fig. 1(a) ).",
  "replication_evidence_dois": [
    "10.1073/pnas.2504164122",
    "10.1371/journal.pcbi.1013469",
    "10.1371/journal.pcbi.1012036",
    "10.1093/cercor/bhae378",
    "10.1007/s00422-021-00894-6"
  ],
  "effect_size_source_sentence": null
}

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  "paper:paper-e8c0e080f1f9"
]

Roles of synaptic strengths and delays from VIP to SOM interneurons for attentional modulation in layers 2/3 of the V1 In our model, attentional modulation in the cortical microcircuit occurred via disinhibition, which was based on connections from VIP to SOM interneurons ( Fig. 1(a) ).

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  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
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