Details

scope
human clinical neuroimaging review
section_id
section_07
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-07
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
source_span
In addition to cortical nodes of the SN, the network’s associated subcortical structures, including the dorsal striatum, mediodorsal thalamus and dopaminergic brainstem nuclei, comprise a discrete regulatory loop circuit.
study_system
human clinical neuroimaging review
section_title
Parallel Loop Channels: Motor, Limbic, Associative, and Beyond the Classic Three
evidence_summary
Review of clinical and experimental data shows that the salience network's cortico-striato-thalamo-cortical loop is central to mechanisms of cognitive control and is disrupted across multiple psychiatric illnesses.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-07
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
claim_text
Cortical nodes of the salience network (dorsal anterior cingulate and anterior insula) form a discrete cortico-striato-thalamo-cortical loop with dorsal striatum, mediodorsal thalamus, and dopaminergic brainstem nuclei that supports cognitive control across psychiatric disorders.
raw_fields
{
  "n": 0,
  "doi": "10.3389/fnsys.2016.00104",
  "claim": "Cortical nodes of the salience network (dorsal anterior cingulate and anterior insula) form a discrete cortico-striato-thalamo-cortical loop with dorsal striatum, mediodorsal thalamus, and dopaminergic brainstem nuclei that supports cognitive control across psychiatric disorders.",
  "cite_key": "Peters2016",
  "evidence": "Review of clinical and experimental data shows that the salience network's cortico-striato-thalamo-cortical loop is central to mechanisms of cognitive control and is disrupted across multiple psychiatric illnesses.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "human clinical neuroimaging review",
  "source_cluster_id": "cluster_06",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "In addition to cortical nodes of the SN, the network’s associated subcortical structures, including the dorsal striatum, mediodorsal thalamus and dopaminergic brainstem nuclei, comprise a discrete regulatory loop circuit.",
  "replication_evidence_dois": [
    "10.1146/annurev.ne.09.030186.002041",
    "10.1101/cshperspect.a009621"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-fddf6e2a64b3"
]
evidence_refs
[
  {
    "ref": "paper:paper-fddf6e2a64b3"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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