Using several Cre mouse lines, we performed cellular-resolution Ca 2+ imaging f…

Using several Cre mouse lines, we performed cellular-resolution Ca 2+ imaging from excitatory pyramidal (PYR) neurons as well as three distinct subtypes of inhibitory interneurons: parvalbumin-positive (PV + ), somatostatin-positive (SST + ), and vasoactive intestinal peptide-positive (VIP + ) neurons, which together comprise 85% of all GABAergic neurons in the cortex ( Rudy et al., 2011; Xu et al., 2010 ).

{
  "n": 20,
  "doi": "10.1016/j.neuron.2015.06.021",
  "year": "2015",
  "claim": "Using several Cre mouse lines, we performed cellular-resolution Ca 2+ imaging from excitatory pyramidal (PYR) neurons as well as three distinct subtypes of inhibitory interneurons: parvalbumin-positive (PV + ), somatostatin-positive (SST + ), and vasoactive intestinal peptide-positive (VIP + ) neurons, which together comprise 85% of all GABAergic neurons in the cortex ( Rudy et al., 2011; Xu et al., 2010 ).",
  "title": null,
  "journal": "Neuron",
  "cite_key": "Pinto2015",
  "evidence": "Cell-Type-Specific Activity in Prefrontal Cortex during Goal-Directed Behavior",
  "effect_size": null,
  "text_access": "fulltext",
  "first_author": "Pinto",
  "study_system": "mouse PFC/frontal cortex",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "author_list_short": "Pinto, Dan",
  "replication_status": "replicated",
  "_source_cluster_index": 7,
  "claim_source_sentence": "Using several Cre mouse lines, we performed cellular-resolution Ca 2+ imaging from excitatory pyramidal (PYR) neurons as well as three distinct subtypes of inhibitory interneurons: parvalbumin-positive (PV + ), somatostatin-positive (SST + ), and vasoactive intestinal peptide-positive (VIP + ) neurons, which together comprise 85% of all GABAergic neurons in the cortex ( Rudy et al., 2011; Xu et al., 2010 ).",
  "replication_evidence_dois": [
    "10.1126/science.1254126",
    "10.1038/nn.4554",
    "10.1126/science.aag2599"
  ],
  "effect_size_source_sentence": "Figure 1 Experimental Approach (A) Schematic of the behavioral task. (B) Learning curves of an example mouse (left) and population of imaged mice (right, n = 20)."
}

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  "paper:paper-6fb6c7efe883"
]

Using several Cre mouse lines, we performed cellular-resolution Ca 2+ imaging from excitatory pyramidal (PYR) neurons as well as three distinct subtypes of inhibitory interneurons: parvalbumin-positive (PV + ), somatostatin-positive (SST + ), and vasoactive intestinal peptide-positive (VIP + ) neurons, which together comprise 85% of all GABAergic neurons in the cortex ( Rudy et al., 2011; Xu et al., 2010 ).

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    "Local review repositories are read-only inputs.",
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  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
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