Details
- scope
- mouse S1
- claim_text
- Within the S1, there is a large diversity of cortical interneurons including parvalbumin (PV), somatostatin (SOM) and vasoactive intestinal polypeptide (VIP)-expressing neurons 22 .
- section_id
- section_13
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- effect_size
- 3-fold
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-13-conclusion
- source_kind
- review_finding
- source_path
- evidence/section_13_evidence_package.json
- source_span
- Within the S1, there is a large diversity of cortical interneurons including parvalbumin (PV), somatostatin (SOM) and vasoactive intestinal polypeptide (VIP)-expressing neurons 22 .
- study_system
- mouse S1
- section_title
- Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
- evidence_summary
- Activation of cortical somatostatin interneurons prevents the development of neuropathic pain
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-13-conclusion
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1038/nn.4595", "year": "2017", "claim": "Within the S1, there is a large diversity of cortical interneurons including parvalbumin (PV), somatostatin (SOM) and vasoactive intestinal polypeptide (VIP)-expressing neurons 22 .", "title": null, "journal": "Nature neuroscience", "cite_key": "Cichon2017", "evidence": "Activation of cortical somatostatin interneurons prevents the development of neuropathic pain", "effect_size": "3-fold", "text_access": "fulltext", "first_author": "Cichon", "study_system": "mouse S1", "_source_cluster": "cluster_06_disinhibition_circuit", "author_list_short": "Cichon, Blanck, Gan", "replication_status": "replication_unknown", "_source_cluster_index": 25, "claim_source_sentence": "Within the S1, there is a large diversity of cortical interneurons including parvalbumin (PV), somatostatin (SOM) and vasoactive intestinal polypeptide (VIP)-expressing neurons 22 .", "replication_evidence_dois": [], "effect_size_source_sentence": "In the region of the S1 corresponding to the injured hind limbs of the animals, we found that Ca 2+ activities in the somata of L5 pyramidal neurons (located > 600 μm below the pial surface) were about 3-fold higher in SNI mice in a quiet resting state than in Sham mice at 1 month post-surgery ( Fig." }- source_refs
[ "paper:paper-d00f7f72db9b" ]
- evidence_refs
[ { "ref": "paper:paper-d00f7f72db9b" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }