Details
- scope
- mouse V1
- section_id
- section_13
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- effect_size
- 300 μm
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-13-conclusion
- source_kind
- review_finding
- source_path
- evidence/section_13_evidence_package.json
- study_system
- mouse V1
- section_title
- Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
- evidence_summary
- Vision and Locomotion Shape the Interactions between Neuron Types in Mouse Visual Cortex
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-13-conclusion
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
- claim_text
Modulation of firing by locomotion ( Ayaz et al., 2013; Erisken et al., 2014; Fu et al., 2014; Niell and Stryker, 2010 ) has been suggested to arise from a disinhibitory circuit, where interneurons expressing vasoactive intestinal peptide ( Vip ) inhibit Sst interneurons and thereby disinhibit pyramidal (Pyr) cells.
- raw_fields
{ "n": 843, "doi": "10.1016/j.neuron.2018.03.037", "year": "2018", "claim": "Modulation of firing by locomotion ( Ayaz et al., 2013; Erisken et al., 2014; Fu et al., 2014; Niell and Stryker, 2010 ) has been suggested to arise from a disinhibitory circuit, where interneurons expressing vasoactive intestinal peptide ( Vip ) inhibit Sst interneurons and thereby disinhibit pyramidal (Pyr) cells.", "title": null, "journal": "Neuron", "cite_key": "Dipoppa2018", "evidence": "Vision and Locomotion Shape the Interactions between Neuron Types in Mouse Visual Cortex", "effect_size": "300 μm", "text_access": "fulltext", "first_author": "Dipoppa", "study_system": "mouse V1", "_source_cluster": "cluster_06_disinhibition_circuit", "author_list_short": "Dipoppa, Ranson, Krumin", "replication_status": "independently_replicated", "_source_cluster_index": 11, "claim_source_sentence": "Modulation of firing by locomotion ( Ayaz et al., 2013; Erisken et al., 2014; Fu et al., 2014; Niell and Stryker, 2010 ) has been suggested to arise from a disinhibitory circuit, where interneurons expressing vasoactive intestinal peptide ( Vip ) inhibit Sst interneurons and thereby disinhibit pyramidal (Pyr) cells.", "replication_evidence_dois": [ "10.1016/j.cell.2014.01.050", "10.7554/elife.50340" ], "effect_size_source_sentence": "The average correlation with speed was slightly negative ( ρ g r a y = − 0.05 ± 0.03 , SE) among Pvalb cells in superficial L2/3 (depth < 300 μm, n = 843) and weakly positive ( ρ g r a y = 0.11 ± 0.04 , SE , n = 831 ) in deeper L2/3. (C) Similar analysis for Vip cells. (D) Similar analysis for Sst cells." }- source_refs
[ "paper:paper-f457e091013f" ]
- source_span
Modulation of firing by locomotion ( Ayaz et al., 2013; Erisken et al., 2014; Fu et al., 2014; Niell and Stryker, 2010 ) has been suggested to arise from a disinhibitory circuit, where interneurons expressing vasoactive intestinal peptide ( Vip ) inhibit Sst interneurons and thereby disinhibit pyramidal (Pyr) cells.
- evidence_refs
[ { "ref": "paper:paper-f457e091013f" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }