Details

scope
mouse S1
section_id
section_13
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
effect_size
p = 0.01
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-13-conclusion
source_kind
review_finding
source_path
evidence/section_13_evidence_package.json
study_system
mouse S1
section_title
Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
evidence_summary
Higher-Order Thalamocortical Inputs Gate Synaptic Long-Term Potentiation via Disinhibition
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-13-conclusion
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
claim_text
Keywords plasticity long-term potentiation LTP thalamus somatosensory barrel cortex BC disinhibition posterior medial complex of the thalamus POm somatostatin-expressing interneurons SST vasoactive-intestinal-peptide-expressing interneurons VIP parvalbumin-expressing interneurons PV Introduction Sensory experience and perceptual learning can remodel neocortical synaptic circuits throughout life ( Feldman, 2009 ).
raw_fields
{
  "n": null,
  "doi": "10.1016/j.neuron.2018.10.049",
  "year": "2019",
  "claim": "Keywords plasticity long-term potentiation LTP thalamus somatosensory barrel cortex BC disinhibition posterior medial complex of the thalamus POm somatostatin-expressing interneurons SST vasoactive-intestinal-peptide-expressing interneurons VIP parvalbumin-expressing interneurons PV Introduction Sensory experience and perceptual learning can remodel neocortical synaptic circuits throughout life ( Feldman, 2009 ).",
  "title": null,
  "journal": "Neuron",
  "cite_key": "Williams2019",
  "evidence": "Higher-Order Thalamocortical Inputs Gate Synaptic Long-Term Potentiation via Disinhibition",
  "effect_size": "p = 0.01",
  "text_access": "fulltext",
  "first_author": "Williams",
  "study_system": "mouse S1",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "author_list_short": "Williams, Holtmaat",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 15,
  "claim_source_sentence": "Keywords plasticity long-term potentiation LTP thalamus somatosensory barrel cortex BC disinhibition posterior medial complex of the thalamus POm somatostatin-expressing interneurons SST vasoactive-intestinal-peptide-expressing interneurons VIP parvalbumin-expressing interneurons PV Introduction Sensory experience and perceptual learning can remodel neocortical synaptic circuits throughout life ( Feldman, 2009 ).",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "RPS+CNO drives LTP, whereas RPS POm-hM4Di +CNO fails to elicit LTP (p = 0.01)."
}
source_refs
[
  "paper:paper-55f18434021b"
]
source_span
Keywords plasticity long-term potentiation LTP thalamus somatosensory barrel cortex BC disinhibition posterior medial complex of the thalamus POm somatostatin-expressing interneurons SST vasoactive-intestinal-peptide-expressing interneurons VIP parvalbumin-expressing interneurons PV Introduction Sensory experience and perceptual learning can remodel neocortical synaptic circuits throughout life ( Feldman, 2009 ).
evidence_refs
[
  {
    "ref": "paper:paper-55f18434021b"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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