Details

scope
mouse PFC/mPFC/frontal cortex
claim_text
Previous studies have shown that VIP neuron activation disinhibits pyramidal neurons by inhibiting SST and PV interneurons 25 , 26 , 34 , 35 .
section_id
section_13
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-13-conclusion
source_kind
review_finding
source_path
evidence/section_13_evidence_package.json
source_span
Previous studies have shown that VIP neuron activation disinhibits pyramidal neurons by inhibiting SST and PV interneurons 25 , 26 , 34 , 35 .
study_system
mouse PFC/mPFC/frontal cortex
section_title
Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
evidence_summary
Delay activity of specific prefrontal interneuron subtypes modulates memory-guided behavior
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-13-conclusion
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": 9,
  "doi": "10.1038/nn.4554",
  "year": "2017",
  "claim": "Previous studies have shown that VIP neuron activation disinhibits pyramidal neurons by inhibiting SST and PV interneurons 25 , 26 , 34 , 35 .",
  "title": null,
  "journal": "Nature neuroscience",
  "cite_key": "Kamigaki2017",
  "evidence": "Delay activity of specific prefrontal interneuron subtypes modulates memory-guided behavior",
  "effect_size": null,
  "text_access": "fulltext",
  "first_author": "Kamigaki",
  "study_system": "mouse PFC/mPFC/frontal cortex",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "author_list_short": "Kamigaki, Dan",
  "replication_status": "replicated",
  "_source_cluster_index": 20,
  "claim_source_sentence": "Previous studies have shown that VIP neuron activation disinhibits pyramidal neurons by inhibiting SST and PV interneurons 25 , 26 , 34 , 35 .",
  "replication_evidence_dois": [
    "10.1126/science.1254126",
    "10.1016/j.neuron.2015.06.021",
    "10.1126/science.aag2599"
  ],
  "effect_size_source_sentence": "1 ), and their correct response rate stabilized at 84 ± 2.6 % (s.e.m., n = 9 mice, Fig."
}
source_refs
[
  "paper:paper-6552e7a00e2e"
]
evidence_refs
[
  {
    "ref": "paper:paper-6552e7a00e2e"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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