- claim_text
Optogenetic inactivation of parvalbumin interneurons in mouse V1 decreases network synchrony and reduces both response reliability and the spatial repertoire of coactive ensembles, identifying PV cells as a sculptor of cortical ensemble structure.
- raw_fields
{
"n": null,
"doi": "10.1093/cercor/bhx169",
"claim": "Optogenetic inactivation of parvalbumin interneurons in mouse V1 decreases network synchrony and reduces both response reliability and the spatial repertoire of coactive ensembles, identifying PV cells as a sculptor of cortical ensemble structure.",
"cite_key": "Agetsuma2018",
"evidence": "Optogenetic PV silencing + simultaneous 2p Ca imaging in mouse V1.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "mouse primary visual cortex (PV interneurons)",
"argument_role": "supporting",
"replication_status": "single_study",
"claim_source_sentence": "But, interestingly, the response reliability and spatial extent of coactive neuronal ensembles during visual stimulation were also disrupted by PV-cell suppression, which reduced the functional repertoire of ensembles.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-bd3acb8f3c56"
]
- evidence_refs
[
{
"ref": "paper:paper-bd3acb8f3c56"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}