Cortical layer-specific critical dynamics triggering perception. Optogenetic ta…

Details

scope: mouse cortex (see paper for region/cell-type detail)
claim_text: Cortical layer-specific critical dynamics triggering perception. Optogenetic targeting of orientation-selective ensembles elicited correct behavioral discrimination.
section_id: section_11
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json
review_repo: ComputationalReviewRecurrence
section_ref: wiki_page:computationalreviewrecurrence-11-pattern-completion
source_kind: review_finding
source_path: evidence/section_11_evidence_package.json
source_span: We observed much larger orange light–evoked GCaMP6m fluorescence signals in ChRmine-expressing neurons compared with other ChR-expressing cells at the same light-exposure duration (,and).
study_system: mouse cortex (see paper for region/cell-type detail)
section_title: 11. Physiological signature III — pattern completion, replay, and sequence generation as recurrent-circuit read-outs in mouse cortex
review_bundle_ref: analysis_bundle:ab-d9c479db9be9
replication_status: single_study
review_package_ref: analysis_bundle:ab-d9c479db9be9
source_artifact_ref: wiki_page:computationalreviewrecurrence-11-pattern-completion
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_11_evidence_package.json
commit_sha: 79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence

Raw fields (5)

raw_fields

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  "doi": "10.1126/science.aaw5202",
  "claim": "Cortical layer-specific critical dynamics triggering perception. Optogenetic targeting of orientation-selective ensembles elicited correct behavioral discrimination.",
  "cite_key": "Marshel2019",
  "evidence": "Cortical layer-specific critical dynamics triggering perception. — Perceptual experiences may arise from neuronal activity patterns in mammalian neocortex. We probed mouse neocortex during visual discrimination using a red-shifted channelrhodopsin (ChRmine, discovered through structure-guided genome mining) alongside multiplexed multiphoton-holography (MultiSLM), a",
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  "study_system": "mouse cortex (see paper for region/cell-type detail)",
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source_refs

[
  "paper:paper-6c94ef0ab8aa"
]

evidence_refs

[
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source_policy

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evidence_summary

Cortical layer-specific critical dynamics triggering perception. — Perceptual experiences may arise from neuronal activity patterns in mammalian neocortex. We probed mouse neocortex during visual discrimination using a red-shifted channelrhodopsin (ChRmine, discovered through structure-guided genome mining) alongside multiplexed multiphoton-holography (MultiSLM), a

Cortical layer-specific critical dynamics triggering perception. Optogenetic ta…

Details

Replication

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