Details

scope
mammal neocortex
claim_text
We found a significant increase in the numbers of both VIP- and Reelin-expressing interneurons in the cortex of Bax- null animals compared with their control littermates ( Figures 1 D–1F).
section_id
section_13
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
effect_size
p = 0.01412
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-13-conclusion
source_kind
review_finding
source_path
evidence/section_13_evidence_package.json
source_span
We found a significant increase in the numbers of both VIP- and Reelin-expressing interneurons in the cortex of Bax- null animals compared with their control littermates ( Figures 1 D–1F).
study_system
mammal neocortex
section_title
Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
evidence_summary
Activity Regulates Cell Death within Cortical Interneurons through a Calcineurin-Dependent Mechanism
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-13-conclusion
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.celrep.2018.01.007",
  "year": "2018",
  "claim": "We found a significant increase in the numbers of both VIP- and Reelin-expressing interneurons in the cortex of Bax- null animals compared with their control littermates ( Figures 1 D–1F).",
  "title": null,
  "journal": "Cell reports",
  "cite_key": "Priya2018",
  "evidence": "Activity Regulates Cell Death within Cortical Interneurons through a Calcineurin-Dependent Mechanism",
  "effect_size": "p = 0.01412",
  "text_access": "fulltext",
  "first_author": "Priya",
  "study_system": "mammal neocortex",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "author_list_short": "Priya, Paredes, Karayannis",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 32,
  "claim_source_sentence": "We found a significant increase in the numbers of both VIP- and Reelin-expressing interneurons in the cortex of Bax- null animals compared with their control littermates ( Figures 1 D–1F).",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Scale bar, 100 μm. (E) Quantification reveals an increase in density of Reelin+ interneurons in Bax cKOs compared with the control. n ≥ 3; p = 0.01412. (F) Quantification reveals an increase in density of VIP+ interneurons in Bax cKOs compared with the control. n ≥ 3; p = 0.001."
}
source_refs
[
  "paper:paper-132ad38dffb8"
]
evidence_refs
[
  {
    "ref": "paper:paper-132ad38dffb8"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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