Details

scope
spiking 4-population microcircuit model
claim_text
Modeling of cortical interneuron subtypes (PV, SST, VIP, NDNF) shows class-specific contributions to trial-by-trial variability, with VIP recruitment increasing variability through gain modulation.
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-12-computational-models
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
source_span
To address this, we investigate the dynamics of stimulus response in a cortical microcircuit model with one excitatory and three inhibitory interneuron populations (PV, SST, VIP).
study_system
spiking 4-population microcircuit model
section_title
Computational Models of VIP Circuit Function
evidence_summary
Spiking 4-population model fitted to V1 imaging variance statistics across conditions.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
single_study
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-12-computational-models
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "id": "cluster_11_finding_90",
  "doi": "10.1038/s42003-023-05231-0",
  "pmid": "37620550",
  "year": "2023",
  "claim": "Modeling of cortical interneuron subtypes (PV, SST, VIP, NDNF) shows class-specific contributions to trial-by-trial variability, with VIP recruitment increasing variability through gain modulation.",
  "pmcid": "PMC10449833",
  "title": "Role of interneuron subtypes in controlling trial-by-trial output variability in the neocortex.",
  "authors": "Guo L, Kumar A.",
  "journal": "Communications biology",
  "cite_key": "Guo2023",
  "evidence": "Spiking 4-population model fitted to V1 imaging variance statistics across conditions.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "spiking 4-population microcircuit model",
  "_source_cluster": "cluster_11_computational_models",
  "replication_status": "single_study",
  "_source_cluster_index": 89,
  "claim_source_sentence": "To address this, we investigate the dynamics of stimulus response in a cortical microcircuit model with one excitatory and three inhibitory interneuron populations (PV, SST, VIP).",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-053c6e0041e2"
]
evidence_refs
[
  {
    "ref": "paper:paper-053c6e0041e2"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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