Details

scope
vip-interneurons
claim_text
Neocortical VIP and SOM interneurons activate as cooperative populations via local excitation, GABAergic disinhibition and gap junctions
section_id
section_13
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-13-conclusion
source_kind
review_finding
source_path
evidence/section_13_evidence_package.json
source_span
We demonstrate a variety of synergistic mechanisms, involving population-specific local excitation, GABAergic disinhibition and excitation through electrical coupling, which likely underlie IN population co-activity.
section_title
Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
unevaluated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-13-conclusion
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.neuron.2016.02.037",
  "pmid": "27021171",
  "tags": [
    "locomotion",
    "disinhibition",
    "optogen"
  ],
  "year": "2016",
  "claim": "Neocortical VIP and SOM interneurons activate as cooperative populations via local excitation, GABAergic disinhibition and gap junctions",
  "pmcid": "PMC4961215",
  "title": "Cooperative Subnetworks of Molecularly Similar Interneurons in Mouse Neocortex.",
  "journal": "",
  "citation": "Karnani MM, Jackson J, Ayzenshtat I, Tucciarone J, Manoocheri K, Snider WG, Yuste R.",
  "cite_key": "Karnani2016a",
  "effect_size": null,
  "text_access": "fulltext",
  "citedByCount": 184,
  "isOpenAccess": "N",
  "evidence_type": "mechanism",
  "linked_topics": [
    "locomotion",
    "disinhibition",
    "optogen"
  ],
  "_source_cluster": "cluster_07_in_vivo_function",
  "relevance_score": 0.9,
  "replication_status": null,
  "_source_cluster_index": 9,
  "claim_source_sentence": "We demonstrate a variety of synergistic mechanisms, involving population-specific local excitation, GABAergic disinhibition and excitation through electrical coupling, which likely underlie IN population co-activity."
}
source_refs
[
  "paper:paper-d405e5906927"
]
evidence_refs
[
  {
    "ref": "paper:paper-d405e5906927"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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