Details
- scope
- spiking model of auditory cortex
- claim_text
- Auditory-cortex spiking model with three interneuron classes shows that VIP-mediated disinhibition shapes context-dependent responses and explains experience-dependent plasticity.
- section_id
- section_12
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-12-computational-models
- source_kind
- review_finding
- source_path
- evidence/section_12_evidence_package.json
- study_system
- spiking model of auditory cortex
- section_title
- Computational Models of VIP Circuit Function
- evidence_summary
- Conductance-based spiking circuit; perturbation of VIP→SST synapse alters predicted tuning shifts.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated_independent
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-12-computational-models
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- raw_fields
{ "n": null, "id": "cluster_11_finding_92", "doi": "10.1371/journal.pcbi.1008016", "pmid": "32716912", "year": "2020", "claim": "Auditory-cortex spiking model with three interneuron classes shows that VIP-mediated disinhibition shapes context-dependent responses and explains experience-dependent plasticity.", "pmcid": "PMC7410340", "title": "A circuit model of auditory cortex.", "authors": "Park Y, Geffen MN.", "journal": "PLoS computational biology", "cite_key": "Park2020", "evidence": "Conductance-based spiking circuit; perturbation of VIP→SST synapse alters predicted tuning shifts.", "effect_size": null, "text_access": "fulltext", "study_system": "spiking model of auditory cortex", "_source_cluster": "cluster_11_computational_models", "replication_status": "replicated_independent", "_source_cluster_index": 91, "claim_source_sentence": "The three-unit model was developed to reproduce the compensating mechanisms of the single-unit model: PV suppression results in constant disinhibition for repeated tones, and SST suppression results in a compensating effect from PVs before adaptation that weakens as adaptation strengthens.", "replication_evidence_dois": [ "10.7554/elife.55130", "10.1523/jneurosci.1369-21.2021", "10.1038/s41598-017-01830-0", "10.1371/journal.pcbi.1013306", "10.1016/j.neuron.2021.11.016" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-72a15d353d01" ]
- source_span
The three-unit model was developed to reproduce the compensating mechanisms of the single-unit model: PV suppression results in constant disinhibition for repeated tones, and SST suppression results in a compensating effect from PVs before adaptation that weakens as adaptation strengthens.
- evidence_refs
[ { "ref": "paper:paper-72a15d353d01" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }