Details

scope
vip-interneurons
claim_text
Sound suppresses V1 L2/3 VIP cells preferentially at preferred orientation, contributing to cross-modal sharpening of orientation tuning
section_id
section_13
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-13-conclusion
source_kind
review_finding
source_path
evidence/section_13_evidence_package.json
source_span
L1 neurons were strongly innervated by A1-V1 axons and excited by sound, while visual responses of L2/L3 vasoactive intestinal peptide (VIP) neurons were suppressed by sound, both preferentially at the cell's preferred orientation.
section_title
Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
unevaluated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-13-conclusion
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.neuron.2016.01.027",
  "pmid": "26898778",
  "tags": [
    "disinhibition",
    "optogen"
  ],
  "year": "2016",
  "claim": "Sound suppresses V1 L2/3 VIP cells preferentially at preferred orientation, contributing to cross-modal sharpening of orientation tuning",
  "pmcid": "PMC4874809",
  "title": "Cross-Modality Sharpening of Visual Cortical Processing through Layer-1-Mediated Inhibition and Disinhibition.",
  "journal": "",
  "citation": "Ibrahim LA, Mesik L, Ji XY, Fang Q, Li HF, Li YT, Zingg B, Zhang LI, Tao HW.",
  "cite_key": "Ibrahim2016",
  "effect_size": null,
  "text_access": "fulltext",
  "citedByCount": 233,
  "isOpenAccess": "N",
  "evidence_type": "mechanism",
  "linked_topics": [
    "optogen",
    "disinhibition"
  ],
  "_source_cluster": "cluster_07_in_vivo_function",
  "relevance_score": 0.8,
  "replication_status": null,
  "_source_cluster_index": 5,
  "claim_source_sentence": "L1 neurons were strongly innervated by A1-V1 axons and excited by sound, while visual responses of L2/L3 vasoactive intestinal peptide (VIP) neurons were suppressed by sound, both preferentially at the cell's preferred orientation."
}
source_refs
[
  "paper:paper-1a4df0a84e5a"
]
evidence_refs
[
  {
    "ref": "paper:paper-1a4df0a84e5a"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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