A dendritic-substrate model of cortical inhibition shows that distinct dendriti…

{
  "n": null,
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  "doi": "10.1101/2024.07.09.602783",
  "pmid": "",
  "year": "2024",
  "claim": "A dendritic-substrate model of cortical inhibition shows that distinct dendritic compartments of pyramidal cells receive temporally diverse inhibition from PV, SST, and VIP/NDNF subtypes.",
  "pmcid": "",
  "title": "A dendritic substrate for temporal diversity of cortical inhibition",
  "authors": "Morabito A, Zerlaut Y, Dhanasobhon D, Berthaux E, Tzilivaki A, Moneron G, Cathala L, Poirazi P, Bacci A, DiGregorio D, Lourenço J, Rebola N.",
  "journal": "bioRxiv (Cold Spring Harbor Laboratory)",
  "cite_key": "Morabito2024",
  "evidence": "Authors developed a compartmental model of dendritic temporal inhibition in cortical pyramidal cells and report VIP-related disinhibition / interneuron-circuit dynamics consistent with the canonical VIP→SST→pyramidal motif.",
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  "text_access": "abstract_only",
  "study_system": "compartmental model of dendritic temporal inhibition in cortical pyramidal cells",
  "_source_cluster": "cluster_11_computational_models",
  "replication_status": "replicated_independent",
  "_source_cluster_index": 159,
  "claim_source_sentence": "We confirmed these predictions with <i>in vivo</i> recordings of IN activity in the visual cortex of awake mice, revealing a rapid and linear recruitment of PV-INs as opposed to a long-lasting integrative activation of SST-INs.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

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