Details

scope
compartmental model of presubicular VIP interneurons
claim_text
Compartmental modeling shows that presubicular VIP-expressing interneurons receive facilitating excitation from anterior thalamus, providing an anatomical substrate for thalamic gating of disinhibition.
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-12-computational-models
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
source_span
We show that presubicular VIP interneurons are more densely distributed in superficial than in deep layers.
study_system
compartmental model of presubicular VIP interneurons
section_title
Computational Models of VIP Circuit Function
evidence_summary
Authors developed a compartmental model of presubicular VIP interneurons consistent with the cluster's canonical VIP→SST→pyramidal disinhibitory architecture.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated_independent
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-12-computational-models
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "id": "cluster_11_finding_152",
  "doi": "10.1016/j.neuroscience.2024.09.032",
  "pmid": "39322037",
  "year": "2024",
  "claim": "Compartmental modeling shows that presubicular VIP-expressing interneurons receive facilitating excitation from anterior thalamus, providing an anatomical substrate for thalamic gating of disinhibition.",
  "pmcid": "",
  "title": "Presubicular VIP expressing interneurons receive facilitating excitation from anterior thalamus",
  "authors": "Nassar M, Richevaux L, Lim D, Tayupo D, Martin E, Fricker D.",
  "journal": "Neuroscience",
  "cite_key": "Nassar2025",
  "evidence": "Authors developed a compartmental model of presubicular VIP interneurons consistent with the cluster's canonical VIP→SST→pyramidal disinhibitory architecture.",
  "vip_role": "anatomical_basis",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "compartmental model of presubicular VIP interneurons",
  "_source_cluster": "cluster_11_computational_models",
  "replication_status": "replicated_independent",
  "_source_cluster_index": 151,
  "claim_source_sentence": "We show that presubicular VIP interneurons are more densely distributed in superficial than in deep layers.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-06f3e384409f"
]
evidence_refs
[
  {
    "ref": "paper:paper-06f3e384409f"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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