Details
- scope
- biophysical model of rat L1 cortical interneurons
- claim_text
- Biophysical models of rat layer 1 cortical interneurons show homogeneous narrow-bandwidth spike initiation, constraining theoretical roles for L1 interneurons in disinhibition.
- section_id
- section_13
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-13-conclusion
- source_kind
- review_finding
- source_path
- evidence/section_13_evidence_package.json
- study_system
- biophysical model of rat L1 cortical interneurons
- section_title
- Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
- evidence_summary
- Authors developed a biophysical model of rat L1 cortical interneurons consistent with the cluster's canonical VIP→SST→pyramidal disinhibitory architecture.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- novel
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-13-conclusion
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- raw_fields
{ "n": null, "id": "cluster_11_finding_148", "doi": "10.3389/fncel.2020.00118", "pmid": "32625063", "year": "2020", "claim": "Biophysical models of rat layer 1 cortical interneurons show homogeneous narrow-bandwidth spike initiation, constraining theoretical roles for L1 interneurons in disinhibition.", "pmcid": "PMC7313227", "title": "Homogeneous and Narrow Bandwidth of Spike Initiation in Rat L1 Cortical Interneurons", "authors": "Borda Bossana S, Verbist C, Giugliano M.", "journal": "Frontiers in Cellular Neuroscience", "cite_key": "Bordabossana2020", "evidence": "Authors developed a biophysical model of rat L1 cortical interneurons consistent with the cluster's canonical VIP→SST→pyramidal disinhibitory architecture.", "vip_role": "anatomical_basis", "effect_size": null, "text_access": "fulltext", "study_system": "biophysical model of rat L1 cortical interneurons", "_source_cluster": "cluster_11_computational_models", "replication_status": "novel", "_source_cluster_index": 147, "claim_source_sentence": "Using acute brain tissue slices from the rat neocortex, combined with the analysis of an existing database of model neurons, we investigated the dynamical transfer properties of these cells by sampling an entire population of known “electrical classes” and comparing experiments and model predictions.", "replication_evidence_dois": [], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-078e1536e6ef" ]
- source_span
Using acute brain tissue slices from the rat neocortex, combined with the analysis of an existing database of model neurons, we investigated the dynamical transfer properties of these cells by sampling an entire population of known “electrical classes” and comparing experiments and model predictions.
- evidence_refs
[ { "ref": "paper:paper-078e1536e6ef" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }