Details

scope
biophysical model of rat L1 cortical interneurons
claim_text
Biophysical models of rat layer 1 cortical interneurons show homogeneous narrow-bandwidth spike initiation, constraining theoretical roles for L1 interneurons in disinhibition.
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-12-computational-models
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
study_system
biophysical model of rat L1 cortical interneurons
section_title
Computational Models of VIP Circuit Function
evidence_summary
Authors developed a biophysical model of rat L1 cortical interneurons consistent with the cluster's canonical VIP→SST→pyramidal disinhibitory architecture.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
novel
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-12-computational-models
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
raw_fields
{
  "n": null,
  "id": "cluster_11_finding_148",
  "doi": "10.3389/fncel.2020.00118",
  "pmid": "32625063",
  "year": "2020",
  "claim": "Biophysical models of rat layer 1 cortical interneurons show homogeneous narrow-bandwidth spike initiation, constraining theoretical roles for L1 interneurons in disinhibition.",
  "pmcid": "PMC7313227",
  "title": "Homogeneous and Narrow Bandwidth of Spike Initiation in Rat L1 Cortical Interneurons",
  "authors": "Borda Bossana S, Verbist C, Giugliano M.",
  "journal": "Frontiers in Cellular Neuroscience",
  "cite_key": "Bordabossana2020",
  "evidence": "Authors developed a biophysical model of rat L1 cortical interneurons consistent with the cluster's canonical VIP→SST→pyramidal disinhibitory architecture.",
  "vip_role": "anatomical_basis",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "biophysical model of rat L1 cortical interneurons",
  "_source_cluster": "cluster_11_computational_models",
  "replication_status": "novel",
  "_source_cluster_index": 147,
  "claim_source_sentence": "Using acute brain tissue slices from the rat neocortex, combined with the analysis of an existing database of model neurons, we investigated the dynamical transfer properties of these cells by sampling an entire population of known “electrical classes” and comparing experiments and model predictions.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-078e1536e6ef"
]
source_span
Using acute brain tissue slices from the rat neocortex, combined with the analysis of an existing database of model neurons, we investigated the dynamical transfer properties of these cells by sampling an entire population of known “electrical classes” and comparing experiments and model predictions.
evidence_refs
[
  {
    "ref": "paper:paper-078e1536e6ef"
  }
]
source_policy
{
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  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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