VIP neurons modulate place-cell gain in a brain-region-specific manner predicte…

{
  "n": null,
  "id": "cluster_11_finding_30",
  "doi": "10.7554/elife.54875",
  "pmid": "32598278",
  "year": "2020",
  "claim": "VIP neurons modulate place-cell gain in a brain-region-specific manner predicted by a circuit model with three-interneuron disinhibition.",
  "pmcid": "PMC7324160",
  "title": "Inhibition stabilization is a widespread property of cortical networks.",
  "authors": "Sanzeni A, Akitake B, Goldbach HC, Leedy CE, Brunel N, Histed MH.",
  "journal": "eLife",
  "cite_key": "Sanzeni2020",
  "evidence": "Optogenetic VIP activation increases place-cell firing rates region-specifically; matched by model with regional VIP→SST weights.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "computational model + in vivo VIP-Cre mouse hippocampus",
  "_source_cluster": "cluster_11_computational_models",
  "replication_status": "replicated_independent",
  "_source_cluster_index": 29,
  "claim_source_sentence": "In this section we show that similar results are obtained using a rate model which features input noise and a more biologically accurate transfer function.",
  "replication_evidence_dois": [
    "10.1073/pnas.2504164122",
    "10.1371/journal.pcbi.1013469",
    "10.1371/journal.pcbi.1012036",
    "10.1093/cercor/bhae378",
    "10.1007/s00422-021-00894-6"
  ],
  "effect_size_source_sentence": null
}

[
  "paper:paper-d6edd2b57842"
]

[
  {
    "ref": "paper:paper-d6edd2b57842"
  }
]

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}