Details
- scope
- biophysical CA1 model
- claim_text
- Biophysical hippocampal model with cell-type-specific contributions of PV, SST, VIP and CCK interneurons reproduces theta-gamma cross-frequency coupling and reveals VIP disinhibitory contributions to gamma envelope modulation.
- section_id
- section_13
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-13-conclusion
- source_kind
- review_finding
- source_path
- evidence/section_13_evidence_package.json
- source_span
- Common principles in functional organization of VIP/calretinin cell-driven disinhibitory circuits across cortical areas.
- study_system
- biophysical CA1 model
- section_title
- Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
- evidence_summary
- Multi-compartment Hodgkin-Huxley CA1 model with multiple interneuron types; ablation analysis quantifies VIP contribution to theta-gamma coupling.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated_independent
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-13-conclusion
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
- raw_fields
{ "n": null, "id": "cluster_11_finding_46", "doi": "10.1162/netn_a_00427", "pmid": "40161984", "year": "2025", "claim": "Biophysical hippocampal model with cell-type-specific contributions of PV, SST, VIP and CCK interneurons reproduces theta-gamma cross-frequency coupling and reveals VIP disinhibitory contributions to gamma envelope modulation.", "pmcid": "PMC11949547", "title": "Cell-type-specific contributions to theta-gamma coupled rhythms in the hippocampus.", "authors": "Sengupta S, Talidou A, Lefebvre J, Skinner FK.", "journal": "Network neuroscience (Cambridge, Mass.)", "cite_key": "Sengupta2025", "evidence": "Multi-compartment Hodgkin-Huxley CA1 model with multiple interneuron types; ablation analysis quantifies VIP contribution to theta-gamma coupling.", "effect_size": null, "text_access": "fulltext", "study_system": "biophysical CA1 model", "_source_cluster": "cluster_11_computational_models", "replication_status": "replicated_independent", "_source_cluster_index": 45, "claim_source_sentence": "Common principles in functional organization of VIP/calretinin cell-driven disinhibitory circuits across cortical areas.", "replication_evidence_dois": [ "10.1016/j.neuron.2023.11.006", "10.1101/2025.05.13.653877", "10.1101/2024.09.30.615819", "10.1016/j.neuron.2018.03.037", "10.1523/eneuro.0235-21.2021" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-7a933b7da09d", "paper:paper-d2eb243f7272" ]
- evidence_refs
[ { "ref": "paper:paper-7a933b7da09d" }, { "ref": "paper:paper-d2eb243f7272" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }