Details
- scope
- mouse V1
- claim_text
- 23060193 10.1038/nature11526 PMC3621107 Askew CE , Lopez AJ , Wood MA , Metherate R Nicotine excites VIP interneurons to disinhibit pyramidal neurons in auditory cortex .
- section_id
- section_13
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- effect_size
- 75% of
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-13-conclusion
- source_kind
- review_finding
- source_path
- evidence/section_13_evidence_package.json
- source_span
- 23060193 10.1038/nature11526 PMC3621107 Askew CE , Lopez AJ , Wood MA , Metherate R ( 2019 ) Nicotine excites VIP interneurons to disinhibit pyramidal neurons in auditory cortex .
- study_system
- mouse V1
- section_title
- Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
- evidence_summary
- VIP interneurons regulate cortical size tuning and visual perception
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-13-conclusion
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1101/2023.03.14.532664", "year": "2023", "claim": "23060193 10.1038/nature11526 PMC3621107 Askew CE , Lopez AJ , Wood MA , Metherate R Nicotine excites VIP interneurons to disinhibit pyramidal neurons in auditory cortex .", "title": null, "journal": null, "cite_key": "Ferguson2023b", "evidence": "VIP interneurons regulate cortical size tuning and visual perception", "effect_size": "75% of", "text_access": "fulltext", "study_system": "mouse V1", "_source_cluster": "cluster_06_disinhibition_circuit", "snowball_origin": "forward_r2", "replication_status": "replicated", "_source_cluster_index": 118, "claim_source_sentence": "23060193 10.1038/nature11526 PMC3621107 Askew CE , Lopez AJ , Wood MA , Metherate R ( 2019 ) Nicotine excites VIP interneurons to disinhibit pyramidal neurons in auditory cortex .", "replication_evidence_dois": [ "10.1016/j.celrep.2023.113088" ], "effect_size_source_sentence": "Cell type-specific expression of caspase caused rapid cell death in >75% of VIP-INs in V1 within two weeks of viral injection ( SFig." }- source_refs
[ "paper:paper-0715496b8f46" ]
- evidence_refs
[ { "ref": "paper:paper-0715496b8f46" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }